Cervical secretions from 157 women were examined for antibody against Neisseria gonorrhoeae by an indirect immunofluorescent antibody test. Antigonococcal antibody was detected in 73 (97%) of 75 infected women, being of the IgG class in 73 (97%), of the IgA class in 71 (95%), and of the IgM class in 29 (39%). IgM antibody was nearly always associated with infections of less than 15 days' durati...

BACKGROUND The Oxford-Family Planning Association (Oxford-FPA) contraceptive study has provided information on many serious diseases of the female reproductive tract. No information has been published about a number of common minor conditions. This report fills the gap with regard to uterine polyp, cervicitis, cervical erosion, and vaginitis and vulvitis. METHODS The Oxford-FPA study includes...

An open clinical trial was conducted with V-Gel on 31 patients with vaginitis in the age group of 24-62 years. After initial screening of symptomatology and aetiological organisms the patients were enrolled in the trial. All the patients were advised to apply V-Gel twice daily for a period of 2 weeks. A weekly follow-up was done in all the patients to assess the clinical response and side effec...

OBJECTIVES To study the treatment efficacy of tetracyclines and azithromycin in Mycoplasma genitalium positive patients attending an STD clinic. METHODS All M genitalium positive patients (34 men and 26 women) attending an STD clinic during a 6 month period were treated with antibiotics. All patients known to be partners of M genitalium positive patients and those who were M genitalium positi...

Mezlocillin (2 g) was administered by a single intravenous injection to 32 male patients with gonorrheal urethritis and to five female patients with gonorrheal cervicitis, none of whom had received any pre-treatment or had had any complications. The results of the treatment were "good" in 32 cases (86.5%), "fair" in three (8.1%) and "poor" in two patients (5.4%). One of the two "poor" cases sho...

An open clinical trial was conducted in twenty six women suffering from vaginitis and cervicitis. After confirming the clinical and microbiological diagnosis, all the females were given V-Gel, which was recommended to be applied topically on the vagina and cervix, twice daily for 15 days. The soreness of cervix, pruritus, inflammation of vulva, vaginal discharge was significantly reduced within...

CONTEXT Black women are disproportionately infected with gonorrhea and chlamydia. Because of the potential impact of these infections on women's reproductive health, it is important to determine whether different factors are predictive of infection in women of different races. METHODS Data from 31,762 women aged 15-24 who were tested for gonorrhea and chlamydia at Missouri family planning cli...

Azithromycin (Zithromax), Pfizer, Inc., New York, NY) is a 15-membered-ring macrolide and the first azalide antibiotic. It is distinguished from other macrolides by its rapid and extensive penetration into intracellular and interstitial tissue compartments, accompanied by prolonged tissue and serum half-lives. Azithromycin shares the gram-positive activity of erythromycin but is more potent aga...

BACKGROUND Diseases of the cervix are common in young sexually active women. Non-neoplastic diseases are predominantly inflammatory and are common but there are a few publications on the subject compared to neoplastic diseases of the cervix. MATERIALS AND METHODS The surgical day books of the Histopathology department of the Obafemi Awolowo University Teaching Hospitals Complex Ile-Ife, Niger...