The polysaccharide and flavonoid concentrations of two-, three-, and four-year-old Aloe vera were determined, and their antioxidant activities were evaluated compared to BHT and alpha-tocopherol by the DPPH radical scavenging method and the linoleic acid system at 100 microg of soluble solids per mL of ethanol. The results showed that three-year-old Aloe vera contained significantly higher leve...

Objective: Sulphur mustard (SM), chemically 2,2'-dichloro diethyl sulphide, is an incapacitating and extremely toxic chemical warfare agent, and causes serious blisters on contact with human skin. SM forms sulphonium ion in the body that alkylates DNA and several other macromolecules, and induces oxidative stress. The aim of this study was to evaluate the protective effect of Aloe vera L. gel a...

We analyzed the effect of hydroxyurea on the JAK2V617F allelic ratio (%JAK2V617F), measured in purified blood granulocytes, of patients with polycythemia vera and essential thrombocythemia. Thirty-six patients were examined sequentially prior to and after start of hydroxy-urea therapy (8 polycythemia vera, 17 essential thrombocythemia), or while remaining untreated (2 polycythemia vera, 9 essen...

BACKGROUND Polycythemia vera is a clonal hematopoietic stem cell disorder in which the JAK2 V617F mutation is observed in >95% of patients, but an as yet unidentified process appears to initiate the clonal expansion of hematopoiesis. Because microRNA regulate hematopoietic differentiation, we hypothesized that dysregulated expression of microRNA may contribute to the pathophysiology of polycyth...

This work is a part of a study on the processing of fruit nectars enriched with Aloe vera gel. The aim of this study was to produce therapeutic and high nutritional mango nectar by supplementation of mango pulp with Aloe vera gel. Effects of different addition levels of Aloe vera gel (5, 10, 15, 20 and 25%) on the physical, microbial and chemical properties such as total soluble solids, total a...

Aloe vera is used worldwide for several medical purposes as alternative medicine. The present study was aimed to evaluate the antidiabetic, antihyperlipidemic and antioxidative activity of aloe vera gel extract in diabetic and control rats. Forty male albino rats, weighing (95±5g) were divided into four groups; group 1: normal control, group 2: Diabetic control group (by Intraperitoneal injecti...

BACKGROUND Cytoplasmic mRNA localization is a widespread mechanism for restricting the translation of specific mRNAs to distinct regions of eucaryotic cells. This process involves specific interactions between cellular factors and localization signals in the 3' untranslated regions of the localized mRNA. Because only a few of these cellular factors have been identified, it is not known whether ...

BACKGROUND The role of the environment in the origin of polycythemia vera has not been well documented. Recently, molecular diagnostic tools have been developed to facilitate the diagnosis of polycythemia vera. A cluster of patients with polycythemia vera was suspected in three countries in eastern Pennsylvania where there have long been a concern about environment hazards. METHODS Rigorous c...

STATEMENT OF THE PROBLEM Herpes simplex virus (HSV) infection is one of the most common and debilitating oral diseases; yet, there is no standard topical treatment to control it. The extract of Aloe vera leaves has been previously reported to have anti-inflammatory, antibacterial, and also antiviral effects. There is no data on anti-Herpes simplex virus type 1 (HSV-1) activity of Aloe vera gel....

Background: Stress has different effects on the body and endocrine system. Objectives: The main aim of this study is to determine the effects of immobilization stress and Aloe vera extract on levels of TSH, T3 or T4 in male rats. Materials and Methods: In this experimental study, 90 male Wistar rats were randomly divided into 9 groups of control, receiving normal saline, receiving Aloe vera ext...