Nephrolithiasis is one of the most frequent urologic diseases. The aim of this paper is to study the composition and frequency of 8854 patient kidney stones and in a subset of them their metabolic risk factors to be related to their type of calculi. Physicochemical and crystallographic methods were used to assess kidney stone composition. In a subset of 715 patients, we performed an ambulatory ...

Introduction Research into the aetiology of calculus disease has failed to reveal the fundamental cause of stone formation, but it is apparent that various factors predispose to their development. Renal calculi are likely to occur in most diseases in which there is an increased urinary excretion of crystalloid stone-forming substances. Calcium phosphate and oxalate stones are particularly liabl...

BACKGROUND AND OBJECTIVES Obesity is associated with a higher risk of nephrolithiasis. However, it is not known whether higher body fat mass or abnormal fat distribution influences stone risk independent of dietary factors. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS In this cross-sectional study, non-stone-forming men with no known kidney disease and with a wide range of body weight collec...

A 46-year-old female had a history of recurrent uric acid stone formation, but the reason why uric acid precipitated in her urine was not obvious, because the rate of urate excretion was not high, urine volume was not low, and the pH in her 24-h urine was not low enough. In his discussion of the case, Professor McCance provided new insights into the pathophysiology of uric acid stone formation....

From the analysis of various urinary constituents and the estimation of serum parameters, it is now possible to identify the risk factors responsible for or contributing for stone formation metabolic factor included calcium, oxalate, uric acid, citrate and pH. Environmental factors where total volume, sodium, phosphate and magnesium. Urinary citrate and magnesium found to be lower in stone form...

PURPOSE Exposure to the microgravity environment of space increases the risk of kidney stone formation, particularly for calcium oxalate and uric acid stones. This study was performed to evaluate the efficacy of potassium alkali as potassium-magnesium citrate in reducing renal stone risk and bone turnover. MATERIALS AND METHODS This study was performed as a double-blind, placebo controlled tr...

OBJECTIVES To evaluate the ability of non contrast computed tomography (NCCT) to predict stone composition and fragility for treatment with extracorporeal shock wave lithotripsy (ESWL). METHODS 27 stones of about 10 mm from patients who had undergone different endourological procedures were collected. All patients had been evaluated with NCCT. To perform in vitro ESWL an experimental device w...

The metabolic syndrome describes a cluster of metabolic features that increases the risk for type 2 diabetes mellitus and cardiovascular disease. The prevalence of uric acid nephrolithiasis is higher among stone-forming patients with features of the metabolic syndrome such as obesity and/or type 2 diabetes mellitus. The major determinant in the development of idiopathic uric acid stones is an a...

background: the presence of hyperuricemia and renal function impairment, especially in the absence of urate stone formation is strongly suggestive of lead nephropathy. the evaluation of this association is essential in areas where lead exposure is still prevalent and uncontrolled. objective: to determine the relationship between serum uric acid and renal function indices in lead-exposed workers...