Abstract While SARS-CoV-2 is causing modern human history’s most serious health crisis and upending our way of life, clinical basic research on the virus advancing rapidly, leading to fascinating discoveries. Two studies have revealed how viral virulence factor, nonstructural protein 1 (Nsp1), binds ribosomes inhibit host cell translation. Here, we examine main conclusions molecular activity Ns...

Geographers engaging with policy debates on armed conflict in the Global South are confronted a set of difficult questions that have no satisfying answers. In this provocation, I discuss three risks appear inherent to engagement domain: first is contributing reproducing rather than upending deeply unjust and unequal world order; second reinforcing colonial structures epistemologies; third facil...

Cynthia Lee has written a hard-hitting and insightful book on bias and the law of homicide. Her purpose is to document how murder law’s “reasonable person” may absorb the unreason of prejudice in its various forms (from biases of race to gender to sexual orientation). Doctrinally, Lee’s book is wide-ranging and ambitious, covering a variety of standard defenses, such as provocation (chs. 1–3) a...

Over time, there haven't been many significant challenges to the higher education model. Even if organization of lectures and learning experiences has changed due incorporation increasingly sophisticated technologies, study themes are still evolving. The work being given here is an analysis blockchain technology its potential applications in field education, with a focus on for upending current...

Research on immigration, educational achievement, and ethnoraciality has followed the lead of racialization and assimilation theories by focusing empirical attention on the immigrantorigin population (immigrants and their children), while overlooking the effect of an immigrant presence on the third-plus generation (U.S.-born individuals of U.S.-born parents), especially its white members. We de...

BACKGROUND Improvements in oocyte cryopreservation techniques and establishment of cryopreserved donor oocyte banks have led to improved access to and lower cost of donor oocytes, upending the traditional practice of fresh oocyte donation. The objective of this study was to examine national trends in utilization and live birth rates with fresh versus cryopreserved donor oocytes. METHODS A ret...

T echnologies have a way of unexpectedly upending established social practices, often at a pace far outstripping the ability of a given society to absorb or process disruptions with awareness. From stirrups to gunpowder to magnets, history teaches that even seemingly mundane objects have the capacity to change everything.1 Physical computing has become an umbrella term whose practitioners draw ...

The human rights arguments that underpinned the fight against HIV over the last three decades were poised, but ultimately failed, to provide a similar foundation for success against multidrug-resistant TB (MDR-TB) and other diseases of the poor. With more than 1.5 million deaths since 2000 attributed to strains of MDR-TB, and with half a million new, and mostly untreated, MDR-TB cases in the wo...

Abstract While quantitative methods are routinely used to examine historical materials, critics take issue with the use of global regression models that attach a single parameter each predictor, thereby ignoring effects time and space, which together define context in events unfold. This problem can be addressed by allowing for heterogeneity, as highlighted proliferation work on time-varying mo...

Digital Transformation is upending businesses everywhere. While there ample research on this topic, a clear gap when it comes to understanding the changing talent management role of senior executives in digital transformation processes and demands individual employees. This article relies 23 in-depth interviews with managers who are leading all or some efforts their respective organizations. Ou...