Microiontophoresis of neuroactive substances during single unit recording in awake behaving animals can significantly advance our understanding of neural circuit function. Here, we present a detailed description of a method for constructing carbon fiber multibarrel electrodes suitable for delivering drugs while simultaneously recording single unit activity from deep structures, including brains...

introduction: although tolerance to and dependence on opioids are characterized by excessive activity of camp pathway in some brain stem nuclei, the impact of morphine dependence on activity of camp pathway in paragigantocellularis nucleus (pgi), located in the rostral ventrolateral medulla, remains unclear. therefore, the effect of adenyl cyclase activator forskolin on spontaneous firing rate ...

The purpose of this study was to obtain a better understanding of neuronal responses to correlated input, in particular focusing on the aspect of synchronization of neuronal activity. The first aim was to obtain an analytical expression for the coherence between the output spike train and correlated input and for the coherence between output spike trains of neurons with correlated input. For Po...

A commander and his staff have to use whatever information is available to arrive at an understanding of the situation that can serve as a basis for action, hence sensemaking has a central role in the C2 process. This paper reports the results of a first experimental study of the sensemaking process in a command team. The participants were 99 Army captains studying at the Swedish National Defen...