Background: In this study, we examined a new two step induction protocol for improving the differentiation of human umbilical cord blood-derived mesenchymal stem cells into neural progenitor cells. Materials and Methods: Human umbilical cord blood-derived mesenchymal stem cells were first cultured in Dulbecco’s modified eagle medium supplemented with 10% fetal bovine serum in a humidified incu...

Umbilical cord blood is the baby's blood left over in the umbilical cord and placenta after a baby is delivered and the cord is cut. Cord blood has all of the features of regular blood, but it is also a rich source of hematopoietic stem cells. Hematopoietic stem cells are unspecialized cells that produce all blood cells. These include: • Platelets, which are needed for blood clotting • Red...

abstractbackground: fetal bovine serum (fbs) is widely used in cell culture laboratories,risk of zoonotic infections and allergic side effects create obstacles for its use inclinical trials. therefore, an alternative supplement with proper inherent growthpromotingactivities is demanded.objective: to find fbs substitute, we tested human umbilical cord blood serum(hucs) for proliferation of human...

backgroundresistin is reported as an antagonistic hormone of insulin and in the literature. nowadays, importance of resistin is being more highlighted in the metabolism of mother and fetus during pregnancy. this study aimed to assess the level of resistin in the umbilical cord and blood sugar at birth and evaluate the association of resistin and neonatal birth weight.materials and methodsthis c...

background: abnormal umbilical cord ph can be indicated a distress imposed of newborn and can also be useful in determining the prognosis of the newborn. there are different views about the effect of the neonatal delivery method on the blood gas analysis of the umbilical artery. this study aimed to determine the effect of the method of delivery on umbilical artery ph. methods: in this cross –se...

a quasi experimental study was conducted in the labour rooms of one of the hospital's of the university of   medical science of iran, to compare the effect ofcord blood drainage and oxytocin injection into the umblicat   vein in the duration of the third stage of labour.   a total of 180 women in the course of normal pregnancies with no complications and normal vaginal   dd ivery were sele...

Cord blood hematopoietic stem cells are widely used as an alternative source for hematopoietic stem cells transplant. Increasing rate of patients who need hematopoietic stem cells transplant and many advantages of cord blood in comparison to bone marrow hematopoietic stem cells, have promoted banking of cord blood units. Cord blood banking requires accurate steps in donor selection, cord blood ...