background: to achieve multiple oocytes for in vitro fertilization, ovulation induction is induced by gonadotropins however, it has several effects on oocytes and embryo quality and endometrium receptivity. the aim of this study was to assess ultrastructural changes of corpus luteum after ovarian induction using human menopausal gonadotropin (hmg) and human chorionic gonadotropin (hcg) during l...

Both microvascular damage and myocardial cell injury occur after coronary occlusion, but the relationship of these two events is unclear; specifically, it is unknown whether microvascular damage causes myocardial cell injury. Dogs were subjected to coronary occlusion for 20, 40, 60, 90 or 180 minutes, after which subendocardial and subepicardial biopsies were obtained for electron and light mic...

Autohemotherapy is the most used method to administer O2-O3 systemically. It consists in exposing a limited amount of blood gaseous and reinfusing it, thus activating cascade biochemical pathways involving plasma cells that gives rise antioxidant anti-inflammatory responses. The therapeutic effects strictly depend on O3 dose; it therefore necessary understand relationship between concentration ...

The phosphodiesterase inhibitor tetrahydrophthalazinone NPD-008 was explored by phenotypic in vitro screening, target validation, and ultrastructural approaches against Trypanosoma cruzi . displayed activity different forms strains of T. (50% effective concentration [EC 50 ], 6.6 to 39.5 μM). Increased cAMP levels its combination with benznidazole gave synergistic interaction.

Selective extraction of specific cell components by enzyme or acid hydrolysis is possible from ultrathin sections for electron microscopy and parallel 2 micro sections for light microscopy of tissues fixed in formalin and embedded in a water-soluble polyepoxide, product X133/2097. Normal rat tissues fixed 15 minutes in formalin at 3 degrees C are more rapidly digested by proteinases than those ...

BACKGROUND Neuroblastoma is the most common solid tumour of infancy and is responsible for 15% of childhood cancer deaths. Presence of amplified MYCN in neuroblastoma is associated with poor prognosis and rapid tumour progression. The aim of this study was to examine and compare the ultrastructural features of high-risk MYCN amplified neuroblastomas, with lower-risk non-MYCN amplified tumours. ...