â  background : primary sclerosing cholangitis (psc) is a chronic cholestatic disease that results in segmental stenosis of the bile ducts, cholestasis and fibrosis. during the previous two decades, patients with steroid responsive psc have been presented in a few case reports and studies. this study aims to evaluate and compare igg4 levels in patients with ulcerative colitis (uc), with and wit...

background: musculoskeletal manifestations (msm) of inflammatory bowel diseases (ibds) are usually the most frequent extraintestinal manifestations. however, they are not paid enough attention during regular office visits. this cross-sectional study aimed to draw a clinical picture of msm and their relationships with other findings in patients with ibd. materials and methods: patients of our ib...

BACKGROUND AND AIMS Those who have had an appendicectomy have a reduced risk of developing ulcerative colitis. However, the effect of appendicectomy on disease activity in patients with ulcerative colitis has not been established. METHODS We used the Danish National Patient Registry to identify all incident cases of ulcerative colitis in Denmark during the period 1981 to 1999. Of these, 202 h...

introduction eccrine poroma is a benign neoplasm thought to derived from eccrine sweat glands. recently, studies have shown wide distribution of eccrine poroma, including acral, face, and abdomen forms. case presentation we reported a 65-years-old woman with rapidly growing 5-cm ulcerative eccrine poroma with active bleeding since one year prior to presentation. conclusions although rapid growt...

ulcerative colitis is a chronic disease that specifically affects the mucosa of the rectum and colon. although the etiology of this recurring inflammatory disorder remains essentially unknown, there have been significant advances in identifying the likely genetic and environmental factors that contribute to its pathogenesis. the clinical course of the disease typically manifests with remissions...

ulcerative colitis (uc) is a nonspecific acute and chronic inflammatory bowel disease that diffusely involves the colonic mucosa. the etiology of uc has not yet been elucidated fully. however, many studies have found that immunologic disorders may play a role in the pathogenesis of uc. in addition, due to an increased frequency of uc in families, especially an increased monozygotic compared wit...

BACKGROUND The main symptom of ulcerative colitis is diarrhoea, which is often accompanied by painful tenesmus and faecal blood and mucus. It sometimes co-occurs with abdominal pain, fever, feeling of fatigue, loss of appetite and weight loss. Some dietary factors have been indicated as important in the treatment of ulcerative colitis. The aim of the study was to analyse the association between...

The family history of patients identified during incidence studies in Leicestershire were investigated and the prevalence and comparative risks calculated; 1254 patients aged 15 to 80 years were sent a questionnaire about their family history. All cases with a positive family history were reviewed and confirmed cases included in the study. In Europeans the standardised prevalence of Crohn's dis...

Colorectal cancer is one of the most common malignancies and the most dreadful long-term complication in patients with ulcerative colitis. The incidence rate of colorectal cancer ranks second among the malignancies all over the world, and the number is still rising. Amid the many risk factors for colorectal cancer, ulcerative colitis is becoming increasingly prominent. The risk of colorectal ca...

BACKGROUND The cause and pathophysiology of ulcerative colitis are both mainly unknown. We have previously used whole-genome microarray technique on biopsies obtained from patients with ulcerative colitis to identify 5 changed mucosal transcripts. The aim of this study was to compare mucosal expressions of these five transcripts in ulcerative colitis patients vs. controls, along with the transc...