Individual cone snail ( Conus sp.) contains thousands of bioactive peptides, but there are limited studies on its antimicrobial peptides (AMPs). Here, we investigated AMPs along with AMP-derived genes in the representative Chinese tubular C. betulinus ) by integration our previously published multi-omics (genomics, transcriptomics, and peptidomics) data. We identified a total 466 putative from ...

The objective of the study was to evaluate the fluoride concentration in bottled water available on the market, in comparison with the values printed on the bottle label. Two hundred and twenty-nine water samples were collected from 35 brands available in several supermarkets, grocery stores and snack bars with high turnover in different regions of the municipality of São Paulo, Southeastern Br...

A retrospective study of 9,335 cases of human leptospirosis in the state of São Paulo, Brazil, diagnosed between 1969 and 1997 showed that the disease is endemic throughout the state. Middle-aged adults, with a range of 20-39 years, were most frequently infected (32.40%). The mean annual incidence was 0.53 per 100,000 population and the disease was more frequent in males (87.0%). Cases occurred...

Acute childhood illness is a universal experience for children and families. This paper presents the central process of a Glaserian grounded theory study which explored family management of acute childhood illness at home. Twenty-nine interviews were conducted with 15 families of children 0-9 years of age. Constant comparative analysis generated the substantive grounded theory 'Containing acute...

The preliminary investigations of crude during resources of sugali tribes of Anantapur district, Andhra Pradesh with their recipes, preparation of drugs, administration, usage form several centuries. Fifty plant crude drugs (species) belong to twenty nine families were collected based on folk-lore knowledge. Botanical name, family name, part used, mode of preparation and administration and purp...

A protein's life inside a cell is usually terminated by the action of proteases that hydrolyse the polypeptide to small peptides or free amino acids. Many proteolytic enzymes are specific for only a few protein substrates, or they mediate highly specialized functions. Promiscuous proteases with broad specificities, however, are generally seques-tered and reside within specialized organelles kno...

There are numerous imaging tests for diagnosing musculoskeletal infection. Radiographs are routinely performed, because even when not diagnostic, they provide an anatomic overview of the region of interest that could influence subsequent procedure selection and interpretation. Magnetic resonance imaging is sensitive and provides superb anatomic detail. Bone scintigraphy accurately diagnoses ost...