background and objectives: typhoid is a major health problem faced by the developing countries like pakistan. more than 20 million cases are reported annually worldwide. currently fluoroquinolones are the drugs of choice to treat typhoid fever. in vivo resistance to fluoroquinolones leading to therapeutic failure is developing rapidly and is becoming a major concern for the clinicians. the obje...

BACKGROUND Salmonella enterica species are enteric pathogens that cause severe diseases ranging from self-limiting gastroenteritis to enteric fever and sepsis in humans. These infectious diseases are still the major cause of morbidity and mortality in low-income countries, especially in children younger than 5 years and immunocompromised adults. Vaccines targeting typhoidal diseases are already...

Non-Typhoidal Salmonellosis (NTS) is a form of salmonellosis that infect human from host-non adapted serotypes salmonella, these salmonella strains are distributed in the environment, water and food via warm blooded animals causing gastroenteritis illnesses mostly, accompanied by high antibiotic resistance profile. In Najaf, camel meat considered one most used for consumption. Yet, studies on d...

The present study was undertaken to examine the status of antimicrobial resistance in Salmonella-associated diseases, by verifying possible emergence of reduced susceptibility to fluoroquinolones in Salmonella isolates and determining the incidence of Plasmodium falciparum-associated co-infection with Salmonella serotypes. Antimicrobial resistance in clinical isolates of Salmonellae was examine...

The development of gastroenteritis caused by non-typhoidal Salmonella (NTS) is mediated the action effectors that belong to Type three secretory systems (T3SS) enterica. These are expressed pathogenicity islands 1 and 2 located in genome. T3SS-1 provide invasion salmonella into host cell, take part inflammatory diarrhea some may act as a predisposing factor oncogenesis leading colorectal cancer...

Salmonella is an enteric pathogen that causes a range of diseases in humans. Non-typhoidal Salmonella (NTS) serovars such as Salmonella enterica serovar Typhimurium generally cause a self-limiting gastroenteritis whereas typhoidal serovars cause a systemic disease, typhoid fever. However, S. Typhimurium isolates within the multi-locus sequence type ST313 have emerged in sub-Saharan Africa as a ...

Recurrent episodes are characteristic of non-typhoidal Salmonella septicemia in the AIDS population and are mainly associated with Salmonella enterica serotype Enteritidis or Salmonella enterica serotype Typhimurium. Since 1987, recurrent nontyphoidal Salmonella bacteremia has been included as an AIDS-defining illness. In the preHAART era, up to 45% of persons with HIV infection will have recur...

background: salmonella enterica serovar typhi, as causative agent of typhoid fever, is one of the most important endemic pathogens. non-typhoidal salmonella serovars, including typhimurium , infantis , and enteritidis are amongst the most prevalent serotypes worldwide and in developing areas such as iran. the aim of this study was to apply a uniplex pcr for rapid detection of salmonella spp., a...

BACKGROUND Despite the clinical significance of Salmonella infections, surveillance data worldwide remains limited and is more so exemplified by the lack of reports from Africa especially in eastern, central and western Africa. This study reports on Salmonella serotypes as significant causes of blood stream infections (BSI) and multidrug antibiotic resistance at Korle-Bu Teaching Hospital in Ac...