نتایج جستجو برای: type i insulin
تعداد نتایج: 2315061 فیلتر نتایج به سال:
Abstract Human insulin-like growth factor I (hIGF-I) is a kind of growth factor with clinical significance in medicine. The major objective of this study is over- production of recombinant human insulin-like growth factor I( rhIGF-I) through a developed process by recruiting effective factors in order to achieve the most recombinant protein. Up to now E. coli expression system has been widely us...
Abstract Human insulin-like growth factor I (hIGF-I) is a kind of growth factor with clinical significance in medicine. The major objective of this study is over- production of recombinant human insulin-like growth factor I( rhIGF-I) through a developed process by recruiting effective factors in order to achieve the most recombinant protein. Up to now E. coli expression system has been widely us...
Background: Diabetic ketoacidosis is an acute complication of diabetes, and a medical emergency that is usually seen in type I diabetic patients. No manifestation of type I diabetes is sometimes diagnosed, particularly in children, and the disorder is accompanied by insulin deficiency, reduced size, and altered mental status. Materials and Methods: This descriptive epidemiological study include...
Hybrid insulin/insulin-like growth factor-I (IGF-I) receptors have previously been described in human placenta, but it has not been possible to study their properties in the presence of classical insulin receptors and type I IGF receptors. To facilitate the purification of hybrids, we produced an anti-peptide monoclonal antibody IGFR 1-2, directed against the C-terminal peptide of the type I IG...
Background and purpose: Hyperglycemia contributes to type 2 diabetes and diabetes vascular complications by reduction of the activity of glyoxalase-I (GLO-I) and elevation of glycation, oxidative stress, and inflammatory markers. Linalool is reported to have beneficial effects on glucose metabolism in animal models of diabetes, so, this study aimed at investigating the effect of linalool on the...
The quality of life children with type I diabetes and lifestyle depend lamentably on the level glucose, frequency, mode administration insulin, peculiarities diet. To a large extent, methods subcutaneous injection, but also insulin by pump are determined therapy, dose administered, body’s response, motor skills, etc.
conclusions camel milk increased insulin level in patients with t2dm and might contribute to glycemic control in t2dm. results mean of insulin concentration was significantly increased from 64.59 to 84.03 pmol/l in the camel milk group during the study (p < 0.05). no significant differences were shown in fasting blood sugar, lipid profile, and blood pressure between the two groups at the end of...
Abstract Introduction: There is limited knowledge available on the metabolism of glucose in the brain, an insulin insensitive organ. Insulin receptors hybridize with insulin like growth factor receptor (IGF-I) to transduce the signals in different areas of the brain. In this article we aimed at investigating whether the expression of IGF-I receptor and IGF-I binding proteins (IGFBP1) is change...
Insulin receptors and Type I insulinlike growth factor (IGF) receptors have a similar structure with a major binding subunit of Mr approximately 130,000 linked by disulfide bonds to other membrane proteins to form a Mr greater than 300,000 complex. Both insulin and Type I IGF receptors also interact with both insulin and IGF, although with different binding affinities. We used a panel of human ...
background: type ii diabetes is known as one of the most important, prevalent, and expensive diseases of mankind. late diagnosis and subsequent delayed initiation of treatment or surveillance of patients create a variety of problems for affected individuals. this has raised increasing concerns for public health authorities throughout the world. in the current study, we aimed to find a new appro...
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