objective(s) the aim of this study was to investigate the presence of per-1-type esbls in drug resistant pseudomonas aeruginosa isolates. materials and methods during one-year period (2008-2009), following isolation and identification of 56 p. aeruginosa, the e-test method was performed for determination of minimal inhibitory concentration of ceftazidim. the isolates that they had mic≥16 µg/ml ...

background and objectives: klebsiella pneumoniae , one of the important causes of nosocomial infections, is the most common extended spectrum β-lactamases (esbls) producing organism. esbls are defined as the enzymes capable of hydrolyzing oxyimino-cephalosporins, monobactams and carbapenems. the aims of this study were to identify esbl-producing k. pneumoniae isolates and detect their antibioti...

objective(s) extended-spectrum beta-lactamase (esbl) producing bacteria have an important role in nosocomial infections. due to the limited availability of information about the molecular epidemiology of esbl producing bacteria in mashhad, we decided to investigate about tem, ctx and shv esbls among urinary escherichia coli isolates in mashhad, a city in northeast iran. materials and methods   ...

introduction: this study is aimed to compare phenotypic test methods and determine antibiotic susceptibility pattern of ampc beta-lactamase producing uropathogenic escherichia coli and klebsiella pneumoniae in clinical isolates. method: e. coli and k. pneumoniae were identified by standard microbiological procedures. screening of ampc beta-lactamase production was done by using cefoxitin disc (...

Beta-lactamase enzymes (BLs) have become the most worrisome mediators of antimicrobial resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have in common the ability to hydrolyze the -lactam rings of one or more members of the penicillins, cephalosporins, cephamycins, carbapenems, and monobactams. Extended-spectrum -lactamases (ESBLs) are a subset of BLs that conf...

At least 30 extended-spectrum beta-lactamases (ESB) have emerged responsible for resistance to indigestible beta-lactams (C3G) since their discovery in West Germany in 1983. Most of them are produced by enterobacteria and essentially K. pneumoniae which appeared susceptible to oxyimino-beta-lactams. A double-disk test was useful to detect such nosocomial isolates of enterobacteria (urines, bloo...