نتایج جستجو برای: type a spermatogonia

تعداد نتایج: 13688682  

Journal: :Endocrinology 2012
Aurore Gely-Pernot Mathilde Raverdeau Catherine Célébi Christine Dennefeld Betty Feret Muriel Klopfenstein Shosei Yoshida Norbert B Ghyselinck Manuel Mark

Vitamin A is instrumental to mammalian reproduction. Its metabolite, retinoic acid (RA), acts in a hormone-like manner through binding to and activating three nuclear receptor isotypes, RA receptor (RAR)α (RARA), RARβ, and RARγ (RARG). Here, we show that 1) RARG is expressed by A aligned (A(al)) spermatogonia, as well as during the transition from A(al) to A(1) spermatogonia, which is known to ...

Journal: :Human reproduction 2005
Jens Ehmcke David R Simorangkir Stefan Schlatt

BACKGROUND Spermatogonial expansion in man and non-human primates has been studied for decades. Controversy persists about the cell type representing the testicular stem cell and the exact kinetics of spermatogonial proliferation. We recently determined the starting point of spermatogenesis and proposed a model for clonal expansion of spermatogonia in adult macaques. Here we want to confirm the...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه لرستان - دانشکده علوم پایه 1392

‎in this article‎, ‎we have focused one some basic and productive information about the properties of spectrum and singular values related to compact operators which are ideals in a c*-algebra of bounded operators‎. ‎considering a two-sided connection between the family of symmetric gauge functions on sequence of singular values of compact operators and symmetric norms on finite dimensional ope...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بیرجند - دانشکده ادبیات و علوم انسانی 1392

in new management approaches, in the organizations with inflexible structure, existing of red tapes and interruptions caused by limitations and also non-compliance with environmental changes, create demotivation among staff. with regard to the influence of job motivational potential and its relationship to the type of organizational structure( enabling and dissuasive), the goal of this research...

Journal: :Endocrinology 1999
A M van Pelt D G de Rooij B van der Burg P T van der Saag J A Gustafsson G G Kuiper

The recently discovered estrogen receptor-beta (ERbeta) is expressed in rodent and human testes. To obtain insight in the physiological role of ERbeta we have investigated the cell type-specific expression pattern of ERbeta messenger RNA (mRNA) and protein in the testis of rats of various ages by in situ hybridization and immunohistochemistry. In fetal testes of rats 16 days postcoitum and test...

Journal: :Development 2000
H Ohta K Yomogida K Dohmae Y Nishimune

To study self-renewal and differentiation of spermatogonial stem cells, we have transplanted undifferentiated testicular germ cells of the GFP transgenic mice into seminiferous tubules of mutant mice with male sterility, such as those dysfunctioned at Steel (Sl) locus encoding the c-kit ligand or Dominant white spotting (W) locus encoding the receptor c-kit. In the seminiferous tubules of Sl/Sl...

Journal: :Reproductive toxicology 2011
Ana Luiza Drumond Connie C Weng Gensheng Wang Helio Chiarini-Garcia Leticia Eras-Garcia Marvin L Meistrich

Spermatogenesis is sensitive to the chemotherapeutic drug cyclophosphamide, which decreases the patients' sperm count. Since the recovery of fertility is dependent on regeneration from stem cells, in the present study we evaluated the ability of cyclophosphamide-exposed stem spermatogonia from mice to regenerate spermatogenesis in situ and after transplantation. When seven doses of cyclophospha...

Journal: :Biology of reproduction 2005
Sarah J Meachem Peter G Stanton Stefan Schlatt

The hormones that regulate spermatogonial development are ill defined, in part due to lack of appropriate experimental models. The photoinhibited hamster model provides a rich source of spermatogonia, thus making it an ideal model to study their control. This study aimed to assess the effects of FSH, in the absence of testosterone, on the reinitiation of Sertoli cell and spermatogonial developm...

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