The risk of venous thrombosis and mortality associated with central catheter (PICC/CICC) for malignant tumor patients is not definite. So, we carried out a systematic review and meta-analysis to evaluate it. Among patients with comparing PICC with CICC, odds ratio (OR) or risk ratio (RR) was calculated with a random effect model meta-analysis. The result of the stratification analysis of 7 stud...

OBJECTIVE The objective of this study was to determine the sequential CT findings of controlled hepatocellular carcinoma (HCC) with main portal vein (MPV) thrombosis with the use of transcatheter arterial chemoembolization and additional intra-arterial cisplatin infusion. MATERIALS AND METHODS From January 2004 to September 2006, 138 patients with HCC invading MPV were referred to the angiogr...

Selective occlusion of tumor vasculature was tested as a therapy for solid tumors in a mouse model. The formation of blood clots (thrombosis) within the tumor vessels was initiated by targeting the cell surface domain of human tissue factor, by means of a bispecific antibody, to an experimentally induced marker on tumor vascular endothelial cells. This truncated form of tissue factor (tTF) had ...

HCC has a high propensity to invade into the portal vein by direct venous extension or metastasis, which may cause tumor thrombosis that occurs in up to 70% of patients. It is well recognized that Portal Vein Tumor Thrombosis (PVTT) is a major detrimental prognosticator in HCC and almost all staging or prognostic systems for HCC include PVTT as an important parameter. Herein, we reported an int...

Patients with cancer have a high risk of deep vein thrombosis and pulmonary embolism, as well developing atrial fibrillation (AF) secondary to antineoplastic treatment. These events poor prognosis depend on factors related the tumor ongoing therapy. They are usually elevated during first 6 months […] How Anticoagulate Heart Failure Cancer?

Results Fifty HIV+/HCV+ coinfected pts (n=44 men (88%), median age 50 years [40-74], median CD4 cell count 334/mm3 [58-1621], n=28 Child A cirrhosis (60%)) developed HCC. Thirty-one (63%) pts presented cirrhosis decompensation before HCC diagnosis. At HCC diagnosis, median serum aFP was 20.4 [1.9-198,900] ng/ml, 38 (76%) pts had a nodular tumor (median main diameter 23.5 [11-70] cm) and 12 (24%...

The patient was a 43-year-old man with chronic hepatitis B without history of hepatocellular carcinoma (HCC), who was first diagnosed with thrombosis in right portal vein trunk and portal vein branches and ruptured esophageal varices in October 2011. He underwent endoscopic variceal ligation, but ruptured repeatedly. Despite anti-coagulant therapy, the thrombosis expanded from right portal vein...

developed the neurological events while on treatment. CNS in volvement in Choriocarcinoma can be due to hemorrhagic metastas, tumor embolization and chemotherapy (especially platinum compounds). CNS thrombotic events are extremely rare. The association between cancer and thrombosis was identified in 1865 and the combination is called as Trousseau syndrome.[2] The mechanisms elucidated include c...

PURPOSE Despite current chemotherapies, pancreatic cancer remains an uncontrollable, rapidly progressive disease. Here, we tested an approach combining a recently described antiangiogenic drug, rapamycin, with standard gemcitabine cytotoxic therapy on human pancreatic tumor growth. EXPERIMENTAL DESIGN Tumor growth was assessed in rapamycin and gemcitabine-treated nude mice orthotopically inje...