نتایج جستجو برای: tumor necrotizing factor alpha

تعداد نتایج: 1332861  

Journal: :iranian red crescent medical journal 0
hamid reza naderi faculty of medicine, department of infectious diseases, mashhad university of medical sciences, mashhad, ir iran; faculty of medicine, department of infectious diseases, mashhad university of medical sciences, mashhad, ir iran. tel: +98-9153145632, fax: +985138591057 fereshte sheybani faculty of medicine, department of infectious diseases, mashhad university of medical sciences, mashhad, ir iran susan rezaei pajand faculty of medicine, department of infectious diseases, mashhad university of medical sciences, mashhad, ir iran

conclusions special high-risk groups, including patients with ltbi, should be treated before receiving tnf-α inhibitors. the tuberculin skin test (tst) is a somewhat cost-effective test for the diagnosis of ltbi. however, its usefulness with respect to false results should be re-evaluated in this situation. results there were somewhat different approaches proposed by various researchers regardi...

Journal: :iranian journal of basic medical sciences 0
morteza ghandadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran atieh mohammadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran javad behravan department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran biotechnology research center, mashhad university of medical sciences, mashhad, iran khalil abnous pharmaceutical research center, department of medicinal chemistry, school of pharmacy, mashhad university of medical sciences, mashhad, iran negin haj-ali department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s): acquisition of tnf-α resistance plays role in the onset and growth of malignant tumors. previous studies have demonstrated that mcf-7 cell line and its doxorubicin resistant variant mcf-7/adr are resistant against the cytotoxic effects of tnf-α. in this study, we investigated the role of akt activation in resistance of mcf-7 and mcf-7/adr against tnf-α cytotoxicity. materials and ...

Journal: :hepatitis monthly 0
yuting cheng department of gastroenterology, qingdao medical college; nanjing medical university, qingdao, china baiquan an department of gastroenterology, qingdao medical college; nanjing medical university, qingdao, china man jiang department of gastroenterology, qingdao municipal hospital, qingdao medical college, nanjing medical university, qingdao, china yongning xin department of gastroenterology, qingdao municipal hospital, qingdao medical college, nanjing medical university, qingdao, china; department of gastroenterology, qingdao municipal hospital, qingdao 266021, china. tel:+86-53288905289, fax: +8653288905293 shiying xuan department of gastroenterology, qingdao medical college; nanjing medical university, qingdao, china

conclusions in the chinese han population that we studied, nafld patients who carry the tnf-α-238 ga polymorphism have an increased risk of developing cad. mechanisms underlying this potentially important association require further investigation. background cardiovascular events account for the main cause of death in patients with non-alcoholic fatty liver disease (nafld), and are largely infl...

2005
Levent Yamenel Mehmet Refik Mas Bilgin Comert Ahmet Turan Isik Sezai Aydin Nuket Mas Salih Deveci Mustafa Ozyurt Ilker Tasci Tahir Unal

INTRODUCTION Acute pancreatitis is a local inflammatory process that leads to a systemic inflammatory response in the majority of cases. Bacterial contamination has been estimated to occur in 30-40% of patients with necrotizing pancreatitis. Development of pancreatic necrosis depends mainly on the degree of inflammation and on the microvascular circulation of the pancreatic tissue. Activated pr...

Journal: :international journal of fertility and sterility 0
roshanak abutorabi azar baradaran fatemeh sadat mostafavi yasaman zarrin farahnaz mardanian

background: the pro-inflammatory cytokine, tumor necrosis factor-alpha (tnf-α), is a pathogenic element for a number of disorders. previous studies have reported that the -1031 t/c and -238 g/a polymorphisms in the promoter region of the tnf-α gene are important factors in reproductive-related disorders. one of the most common gynecological diseases of women during the reproductive years is end...

Journal: :international journal of pediatrics 0
qurratul ann warsi university of california and san francisco, department of epidemiology and biostatistics, 1825 4th street, mission bay, san francisco, ca 94154, usa. meghana kunduru state university of new york medical university, syracuse, ny 13202, usa. manoochehr karjoo suny upstate medical university mirza beg 4associate professor of pediatrics, ivision of pediatric gastroenterology, hepatology, and nutrition, suny upstate medical university, 750 east adams street, syracuse, ny 13210, usa.

crohn’s disease is an inflammatory bowel disease (ibd), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. environmental triggers and interaction of genetic determinants also play an indispensible role. in this case report, we present a pre-pubertal girl with intermittent and refra...

Journal: :iranian journal of basic medical sciences 0
morteza ghandadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran atieh mohammadi department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran javad behravan department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran biotechnology research center, mashhad university of medical sciences, mashhad, iran khalil abnous pharmaceutical research center, department of medicinal chemistry, school of pharmacy, mashhad university of medical sciences, mashhad, iran negin haj-ali department of pharmaceutical biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s): acquisition of tnf-α resistance plays role in the onset and growth of malignant tumors. previous studies have demonstrated that mcf-7 cell line and its doxorubicin resistant variant mcf-7/adr are resistant against the cytotoxic effects of tnf-α. in this study, we investigated the role of akt activation in resistance of mcf-7 and mcf-7/adr against tnf-α cytotoxicity. materials and ...

Journal: :iranian journal of allergy, asthma and immunology 0
ahmad reza ebadian department of periodontology, school of dentistry, mashhad university of medical science, mashhad, iran and department of immunology, bu-ali research institute, mashhad university of medical science, mashhad, iran mehrdad radvar department of periodontology, school of dentistry, mashhad university of medical science, mashhad, iran jalil tavakkol afshari department of immunology, bu-ali research institute, mashhad university of medical science, mashhad, iran naser sargolzaee department of periodontology, school of dentistry, mashhad university of medical science, mashhad, iran azam brook department of immunology, bu-ali research institute, mashhad university of medical science, mashhad, iran rashiin ganjali department of immunology, bu-ali research institute, mashhad university of medical science, mashhad, iran

cytokines play a part in pathogenesis of periodontitis via inflammation phenomenon. aggressive periodontitis (agp) is a multifactorial disease resulting in rapid tooth loss due to severe destruction of tooth supporting apparatus. recently, researchers have focused on genetic susceptibility of periodontitis through investigating the gene variations of cytokines and other components of immune res...

Journal: :iranian journal of basic medical sciences 0
roya yaraee department of immunology, medical school and medicinal plant research center, shahed university, tehran, iran nayere askari department of biology, faculty of basic sciences, shahid bahonar university, kerman, iran mohsen naseri department of pharmacology and department of iranian traditional medicine, medical school, shahed university, tehran, iran

objective(s) using herbal medicines as a complementary treatment method is increasing in wide variety of diseases. ms14-an herbal-marine preparation-is reported to have anti-inflammatory and immunomodulatory activities; however, the mechanism underlying its therapeutic effect is not known. macrophages play an important role in host defense mechanisms and carry out their role by producing variou...

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