background: pleurisy is a common extra pulmonary complication of tuberculosis, but current methods for diagnosing it are fairly crude. here we product a meta-analysis for the available evidence on the ability of tumor necrosis factor-? (tnf-?) in pleural fluid to serve as a diagnostic marker of tuberculous pleurisy (tp). materials and methods: we searched the pubmed, embase, and google scholar ...

Vasculogenic mimicry (VM) is the release of angiogenic factors from tumor cells, leading to morphological changes, migration and proliferation vascular endothelial ultimately neovascularization. The presence VM has been identified in breast cancer, formation also gives cancer a poor prognosis such as drug resistance metastasis. authors focus on role PI3K/Akt signaling pathway, hypoxia-inducible...

background: inflammatory response following surgical trauma has long been a matter of study. results, however, have been varied. we sought to assess changes in the levels of proinflammatory and anti-inflammatory cytokines in patients undergoing laparoscopic and open cholecystectomy and their impact on the clinical outcome of patients concerning the postoperative pain score. methods: the study i...

background the association between tumor necrosis factor-alpha (tnf-α) (-308 g/a) gene polymorphisms and level of tissue destruction and periodontal disease progression is not proved. objectives the present study investigated the stereological parameters of interdental papilla in chronic periodontitis (cp) patients with tnf-α (-308 g/a) gene polymorphisms. materials and methods sixty gingiva sa...

Background and Objectives: Coronary artery disease (CAD) is regarded as the leading cause of morbidity and mortality around the world. Diabetes mellitus (DM) is associated with the development of CAD and increased risk of morbidity and mortality. The goal of this study was to assess the association of tumor necrosis factorα (TNF-α) and high sensitivity C-reactive protein (hsCRP) with CAD severi...

background and aims: plants as medicines have always played a vital role in human life. tumor necrosis factor alpha (tnf)-α is one of the macrophage-derived inflammatory cytokine with pleotropic effects in the inflammation process. some studies have been demonstrated that some of the echinops species have anti-inflammatory activity. in fact, echinops lasilepis is introduced as one of the native...

conclusions the results indicated that there was a positive association between susceptibility to chronic hbv infection and tnf-α polymorphism. in addition, hbv patients carrying -308 gg, -857 cc, and -863 aa genotypes with lower serum levels of tnf-α had an increased risk of infection. background the host genetic background regulates the natural history of chronic hepatitis b virus (hbv) infec...

conclusion: in this study group, tnf-α -238 polymorphism was shown to be different in preeclamptic and non-preeclamptic pregnant women. the aa genotype and the a allele may carry an increased risk for developing of preeclampsia. results: there were significant differences between the two groups in tnf-α genotype at position -238 (p < 0.001). in the preeclamptic group, the frequency of the aa ge...