Key words: interstitial nephritis; retinitis pigmentosa; Renal histology revealed chronic tubulointerstitial nephritis with a diÂuse interstitial cellular infiltrate Bardet–Biedl syndrome. consisting mainly of lymphocytes and plasma cells. There were 41 glomeruli, of which 29 were sclerosed. Immunofluorescence was negative. Electron-micro

OBJECTIVES: Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are two diseases with similar clinical presentations but very different prognoses. Transforming growth factor β1 and monocyte chemoattractant protein-1 have been associated with the development of tissue fibrosis. We examined the development of tubulointerstitial fibrosis and its relationship with Transforming growt...

BACKGROUND Cilostazol is an antiplatelet drug that is widely prescribed for the prevention of secondary stroke. Adverse reactions to cilostazol include headaches, palpitations, and diarrhea. Little is known about the nephrotoxicity of cilostazol, such as acute kidney injury. We report a biopsy-proven case of diffuse tubulointerstitial nephritis induced by cilostazol. CASE PRESENTATION A 69-ye...

BACKGROUND Isolated or predominant tubulointerstitial lupus nephritis is rare. CASE PRESENTATION Here we report the case of a thirty eight years old male who was diagnosed with systemic lupus erythematosus (SLE) according to clinical and laboratory criteria and presented with impaired renal function and non nephrotic range proteinuria. Renal biopsy revealed normal glomeruli but interstitial m...

Background & Objectives: Chronicity of lupus nephritis (LN) should be considered for interaction of cell mediated immunity (CMI) and dendritic cells in glomeruli and tubulointerstitial areas. In this study establishment of immunohistopathological changes of dendritic cells and other immune effector cells in lupus nephritis comparing with non-lupus nephritis was performed. Materials & Methods: ...

A 46-year-old female patient presenting with acute interstitial nephritis and anterior uveitis was admitted. The renal biopsy disclosed the presence of interstitial nephritis, confirming the clinical diagnosis of tubulointerstitial nephritis and uveitis (TINU) syndrome. Treatment with oral steroids was started, with prompt improvement of symptoms and laboratory abnormalities.

Hiroshi Nishi, Akihiro Tojo, Maristela Lika Onozato, Rika Jimbo, Masaomi Nangaku, Hiroshi Uozaki, Kenji Hirano, Hiroyuki Isayama, Masao Omata and Shinya Kaname Nephrol Dial Transplant 2007; 22: 1273–1275; doi:10.1093/ndt/gfl672 In the above article, the name of the last author (Toshiro Fujita) was omitted. The correct author list should read as follows: Hiroshi Nishi, Akihiro Tojo, Maristela Li...

PURPOSE To describe the clinical course and treatment with immunomodulatory agents in patients with tubulointerstitial nephritis and uveitis syndrome. METHODS Retrospective analysis of the charts of six patients with tubulointerstitial nephritis and uveitis syndrome. RESULTS The mean (+/-SD) age was 24.3 (+/-16.5) years, range 13 to 49 years. Four patients were children, and two were adults...

Rivaroxaban is a direct oral anticoagulant that is prescribed for the prevention and treatment of thromboembolisms. Rivaroxaban is cleared renally and a common side effect (1-10%) is renal impairment of unknown pathophysiology. We are the first to describe a case of biopsy-proven acute tubulointerstitial nephritis, most likely caused by rivaroxaban.