background: central nervous system malformations are the second most common congenital malformations after congenital heart diseases. these malformations are associated with many instances of morbidity and mortality which underline the importance of prevention and their early diagnosis. objective: the objective of this study is the diagnosis of neural tube defect (ntds) in the first trimester a...

To assess the possible relationship between an increase in progesterone concentration in cerebrospinal fluid (CSF) and enhancement of spread of spinal anaesthesia, we have measured CSF progesterone concentrations in 134 patients undergoing spinal anaesthesia with hyperbaric amethocaine 8 mg. Patients were allocated to one of five groups according to the gestational period: non-pregnant group (n...

BACKGROUND To identify the socio-demographic differences between a sample of women who present for first-trimester and second-trimester abortion. AIM To determine whether women presenting late (in the second trimester) for abortion differ socio-demographically from those presenting early (in the first trimester). MATERIALS AND METHODS Data over 4 years for women presenting for second-trimes...

Background and Objectives: several investigations have been done to evaluate the effect of Ramadan fasting on fetal and maternal health, which have all led to controversial results. The role of Ramadan fasting time in birth weight is still unclear. This study evaluated the effect of fasting at different periods of pregnancy on birth weight. Methods: 250 pregnant women fasting at least one day d...

context maternal serum human chorionic gonadotropin (hcg) and alpha fetal protein (afp) were originally introduced to detect trisomy 21 and neural tube defects. however, in the absence of aneuploidy or neural tube defects, mid-trimester maternal serum hcg and/or maternal serum afp associated with adverse pregnancy outcomes. pregnancies with unexplained mid-trimester elevation in maternal serum ...

OBJECTIVE To assess whether the maternal serum ADAM12s concentrations are altered in the first and second trimester of pregnancies complicated by rare aneuploides. METHODS ADAM12s was measured by a semi-automated time-resolved immunofluorometric assay in a series of 60 first-trimester cases with trisomy 13, 78 first-trimester cases with Turner's syndrome, 38 first-trimester cases with triploi...

abstract background: gestational diabetes is the second common disorder in pregnancy period, which is detected in 24-28 weeks of gestational age through screening tests in low-risk women. the women with gestational diabetes are prone to prenatal mortality and development of future diabetes. therefore, detection of these individuals in the fi rst trimester and conducting preventive interventions...

objective: comparing sublingual and vaginal misoprostol in second trimester pregnancy termination. materials and methods: in this study 268 women at 12-24 weeks of gestation candidate for pregnancy termination were enrolled. women were randomly divided in two groups. the first group received 400 µg sublingual misoprostol and vaginal placebo and the second group received 400 µg vaginal misoprost...

zinc is one of the most important micronutrient with essential role in biochemical regulation of the body functions. the importance of zinc in pregnancy period was widely studied in various countries. variation in zinc plasma levels during pregnancy needs more investigation, because maternal zinc deficiencies may cause some severe abnormalities in the fetus. in this study the plasma levels of z...

Serum cholesterol, triacylglycerols and low-density lipoprotein (LDL) subfractions were determined in 120 primagravid women during normal gestation (40 in each trimester) and in 20 non-pregnant age-matched controls. LDL subfractions were determined by PAGE, and an LDL score was calculated. The higher the score, the smaller the subfractions. The objective of the study was to determine the effect...