نتایج جستجو برای: trientine
تعداد نتایج: 214 فیلتر نتایج به سال:
Wilson’s disease (WD) is an inherited autosomal recessive disorder that lead to copper accumulation in the liver, brain, cornea, and other organs [1]. WD is treatable by life-long decoppering therapy with the aim of removing excess copper and preventing re-accumulation. This is accomplished with two main groups of drugs: chelating agents, including d-penicillamine (DPA) and trientine, that prom...
A highly effective synthetic route for TE2A was developed and the (64)Cu-labeled TE2A complexes showed higher kinetic inertness and faster clearance than most commonly used TETA analogs.
Two thioarsenates [Co(dien)2]3[As3S6]2 (1, dien = diethylenetriamine) and [Mn(teta)]2As2S5 (2, teta = triethylenetetramine) have been solvothermally synthesized and structurally characterized. 1 consists of isolated cyclic [As3S6]3− anions in a chair-conformation and two different isomeric [Co(dien)2] cations, while 2 consists of neutral [Mn(teta)]2As2S5 moieties built up from saddlelike As2S5 ...
metabolism. In Canada few neurologists see sufficient patients to become confident in managing and treating this disorder. Patients can present with liver and/or neuropsychiatric symptoms and so these few patients are spread across a number of disciplines including pediatric, liver or neurological clinics. There is a paucity of randomized controlled trials (RCTs) and Evidence Based Medicine rev...
In the case of a single point interaction we improve, by using different methods, the existence theorem for the unitary evolution generated by a Schrödinger operator with moving point interactions previously obtained by Dell’Antonio, Figari and Teta.
Wilson's disease (WD), also called hepatolenticular degeneration, is an autosomal recessive inheritance disorder of copper metabolism characterized by the multiple mutations in the ATP-ase 7B gene of chromosome 13q. About half of the WD patients have neurological or psychiatric symptoms. As WD is a kind of medicable or nearly curable neurodegenerative disease in the field of medicine, early con...
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