Dermatophytosis and superficial mycosis are a major global public health problem that affects 20-25% of the world's population. The increase in fungal resistance to the commercially available antifungal agents, in conjunction with the limited spectrum of action of such drugs, emphasises the need to develop new antifungal agents. Natural products are attractive prototypes for antifungal agents d...

This report describes the application of PCR fingerprinting for the identification of species and varieties of common dermatophytes and related fungi utilizing as a single primer the simple repetitive oligonucleotide (GACA)(4). The primer was able to amplify all the strains, producing species-specific profiles for Microsporum canis, Microsporum gypseum, Trichophyton rubrum, Trichophyton ajelloi...

The etiology and prevalence of Tinea Capitis in adults and children was studied in 115 cases. The most common etiologic agent was Trichophyton Violaceum recovered from 82 63% cases, Trichophyton rubrum from 10.4%, Trichophyton tonsurans from 3.47% and Microsporum canis from 3.4% cases. The study includes seventy cases of "blackdot" ringworm of the scalp, four cases of Kerion and forty one cases...

[This retracts the article on p. 57 in vol. 5, PMID: 26322275.].

Chloroform, Methanol and Water extract of Solanum indicum Linn., a widely used food and medicinal plant of Assam, India was investigated for its in vitro antifungal activity against five different dermatophytic fungi viz., Trichophyton mentagrophytes, Trichophyton rubrum, Trichophyton tonsurans, Microsporum gypseum and Microsporum fulvum. Agar well diffusion method was used to determine the inh...

The Sensititre YeastOne antifungal panel was used to test 49 dermatophytes belonging to the species Epidermophyton floccosum, Microsporum gypseum, Microsporum canis, Trichophyton tonsurans, Trichophyton rubrum, and Trichophyton mentagrophytes. The MICs of four antifungals obtained with the Sensititre YeastOne antifungal panel were compared with those obtained by the reference NCCLS microdilutio...

Fungicidal activities of pentachloronitrobenzene and derivatives were tested with Candida albicans, Aspergillus fumigatus, Trichophyton rubrum, Trichophyton mentagrophytes, and Microsporon canis. In relation to pentachloronitrobenzene, no increasing fungistatic activities were found with cysteine derivatives. Rising fungistatic activities were seen with pentachlorophenylmethylsulfone and, in so...

Trichophyton raubitschekii is currently regarded as a synonymous name betokening a variant form of Trichophyton rubrum. Nonetheless, isolates conforming to this morphotaxonomic concept have morphological, physiological and clinical features very different from those of typical T. rubrum. Isolates are mainly obtained from subjects originating from certain tropical and subtropical countries, and ...

A n t i f u n g a l a c t i v i t y o f r h e i n ( 1 , 8 dihydroxyanthraquinone3carboxylic acid) isolated from the ethyl acetate extract of Cassia fistula flower was studied. Rhein inhibited the growth of many fungi such as Trichophyton mentagrophytes (MIC 31.25 μg/ml), Trichophyton simii (MIC 125 μg/ml), Trichophyton rubrum (MIC 62.5 μg/ml) and Epidermophyton floccosum (MIC 31.25 μg/ml).

INTRODUCTION Generalized dermatophytosis, or chronic widespread dermatophytosis, is an uncommon disease most often caused by Trichophyton rubrum in the immunocompromised or chronically ill host. Tinea capitis caused by T rubrum is rare in adult patients and has not, to our knowledge, been described in the HIV/AIDS population. We report the unusual case of a 62-year-old HIV-positive woman with g...