OBJECTIVES We evaluated whether carotid intima-media thickness (CIMT) and the presence or absence of plaque improved coronary heart disease (CHD) risk prediction when added to traditional risk factors (TRF). BACKGROUND Traditional CHD risk prediction schemes need further improvement as the majority of the CHD events occur in the "low" and "intermediate" risk groups. On an ultrasound scan, CIM...

Long-term administration of porcine growth hormone-releasing factor (pGRF(1-29)NH2) and(or) thyrotropin-releasing factor (TRF) was evaluated on serum concentrations of growth hormone (GH) thyroxine (T4) and prolactin (PRL). Twenty-four 12-wk-old female Yorkshire-Landrace pigs were injected at 1000 and 1600 for 12 wk with either saline, pGRF (15 micrograms/kg), TRF (6 micrograms/kg) or pGRF + TR...

tRNA-derived RNA fragments (tRFs), non-coding single-stranded RNAs with 14-35 nt in length, were found to play important roles in gene regulation, even in carcinogenesis. In this study, we investigated the expression of tRF-Leu-CAG in human non-small cell lung cancer (NSCLC) and its function in the cell proliferation and cell cycle of NSCLC. The expression level of tRF-Leu-CAG was detected in N...

OBJECTIVE The aim of the study was to provide criteria that can help to distinguish between GBS-TRF and A-CIDP in the early phase of disease. BACKGROUND The distinction between Guillain-Barré syndrome (GBS) with fluctuations shortly after start of treatment (treatment-related fluctuations, or GBS-TRF) and chronic inflammatory demyelinating polyneuropathy with acute onset (A-CIDP) is difficult...

The role of gamma interferon (IFN-gamma) in T cell-replacing factor (TRF) activity for antigen-specific plaque-forming cell (PFC) responses in vitro was studied using antibodies to murine IFN-gamma (Mu IFN-gamma). TRF activity was present in supernatants (Sn) of Con A- or mixed leukocyte reaction-stimulated murine spleen cells as well as in an IL-2-rich fraction of phytohemagglutinin-stimulated...

In this paper, we define a new and broad family of vector-valued random fields called tempered operator fractional operator-stable (TRF, for short). TRF is typically non-Gaussian generalizes stable stochastic processes. comprises moving average harmonizable-type subclasses that are constructed by tempering (matrix-) homogeneous, matrix-valued kernels in time- Fourier-domain integrals with respe...

objective: oxidative stress that damages proteins result in aging and age related diseases. the aim of this study is to determine the effect of tocotrienol rich fraction (trf) on the expression of proteins in oxidative stress-induced caenohabditis elegans (c.elegans) which has homologous genes to humans. methods: the worms were treated with trf prior to, after and continuously in separate group...

tRNA-derived fragments (tRFs) are a new category of regulatory noncoding RNAs with distinct biological functions in cancers and stress-induced diseases. Herein, we first summarize the classification biogenesis tRFs. tRFs produced from pre-tRNAs or mature tRNAs. Based on incision loci, classified into several types: tRF-1, tRF-2, tRF-3, tRF-5, i-tRF. Some participate posttranscriptional regulati...

objective(s) nonenzymatic glycosylation (glycation) occurs in many macromolecules in aging and diabetes due to exposure of biomolecules to high level of glucose. glycation can changes function, activities and structure of many biomolecules. considering this important role of transferrin (trf) in iron transport and antioxidant activity in plasma this study was carried out to investigate the effe...

PURPOSE To implement a method using a tailored radiofrequency (TRF) pulse with a quadratic phase profile to recover susceptibility-induced signal losses in gradient-recalled echo-planar images (EPI). MATERIALS AND METHODS A functional magnetic resonance imaging (fMRI) experiment for compensation of susceptibility artifacts, known as the TRF pulse EPI sequence (TRF-EPI), was used. TRF pulse co...