past earthquakes have demonstrated that old rc bridges may be seismically vulnerable. bridge responses during the last decades illustrated the necessity of the seismic assessment of bridges especially those which were designed with old codes. in this research an existing concrete bridge representative of the most common bridges in the highway system in iran are studied. push over and nonlinear ...

context:micrornas (mirnas) are a class of short, endogenously-initiated, non-coding rnas that post-transcriptionally control gene expression via translational repression or mrna turnover. mirnas have attracted much attention in recent years as they play critical roles in gene expression and are promising tools with many biotech and therapeutic applications. the molecular mechanisms underlying t...

although antidote development should proceed in an orderly fashion from observation, to experimental and safety studies, to clinical trials, this sequence is not always precisely followed. the development of fomepizole as an antidote for toxic alcohol and glycol poisoning is an example of how this may not be the case. interest in the development of fomepizole was spurred in the 1960s. shortly t...

sloshing is a well-known phenomenon in liquid storage tanks subjected to base or body motions. in recent years the use of multiple vertical baffles for reducing the sloshing effects in tanks subjected to earthquake has not been taken into consideration so much. on the other hand, although some of the existing computer programs are capable to model sloshing phenomenon with acceptable accuracy, t...