toxicity bioassays are important tools to determine biological effects of chemical agents on species. the questions remained on, what effects have been imposed on each of the different molecular site of cells by chemical exposure and how to find a pattern for chemical toxicity. to address the questions, hepg2 cell lines were exposed to the different concentrations of cisplatin for 24 hours to r...

orius albidipennis reuter is an important predator of economic pests in greenhouse. in this studu, investigations were performed on toxicity values of abamectin, spinosad and chlorpyrifos in laboratory (petri dish) and greenhouse (clip cage) conditions. lc50 and lc90 values were determined to both sexes, male and female, by using sas software, and comparisons were made according to ratio of lc5...

dimethoate (organophosphate insecticide) and lambda-cyhalothrin (synthetic pyrithroid) aretwo frequently used pesticides due to their high effectiveness and rapid breakdown into environmentally safeproducts. the aim of this present study was to assess and compare the acute toxicity of dimethoate(rogor30%ec) and lambda-cyhalothrin (5%ec) on labeo rohita (hamilton). acute toxicity bioassay wascar...

b a ckground: the efficacy of essential oil of chenopodium ambrosioides flowering aerial parts and its three main active ingredients was evaluated against blattella germanica male adults. m e t hods: composition of essential oil was determined by gc-ms. topical application bioassay was used to evalu- ate contact toxicity of essential oil and three main components. fumigant toxicity of essential...

This study was undertaken to evaluate the protective efficacy of the antioxidants vitamin E and Trolox (a water-soluble vitamin E derivative) against the toxicity of microcystin-LR (MC-LR), Microcystis aeruginosa aqueous extract (CE), and a reference toxin, menadione sodium bisulfite (MSB), in Artemia franciscana nauplii. This was achieved by using the well-established brine shrimp bioassay. Th...

The H4IIE cell bioassay has proven utility as a screening tool for planar halogenated hydrocarbons (PHHs) and structurally similar chemicals accumulated in organisms from the wild. This bioassay has additional applications in hazard assessment of PHH exposed populations. In this review, the toxicological principles, current protocols, performance criteria, and field applications for the assay a...

It is an urgent priority to establish in vivo bioassays for detection of hazards related to fine particles, which can be inhaled into deep lung tissue by humans. In order to establish an appropriate bioassay for detection of lung damage after particle inhalation, several experiments were performed in rats using quartz as a typical lung toxic particle. The results of pilot experiments suggest th...

Compounds thought to be effective against mosquitoes as either 'insecticides' or 'repellents' have recently been shown to contain properties of both, or possess other behavior-modifying actions. Prompted in part by these reports, we conducted posterior analyses of our data to examine some interrelated statistical issues inherent in our bioassay system. Using a modified K&D module, the responses...