This is the ninth yearly article in Tourette Syndrome Research Highlights series, summarizing selected research reports from 2022 relevant to syndrome. The authors briefly summarize they consider most important or interesting.

Gilles de la Tourette syndrome is a childhood-onset syndrome characterized by the presence and persistence of motor and vocal tics. A dysfunction of cortico-striato-pallido-thalamo-cortical networks in this syndrome has been supported by convergent data from neuro-pathological, electrophysiological as well as structural and functional neuroimaging studies. Here, we addressed the question of str...

Objectives: Tourette syndrome is a disease with vocal and motor tics. This disorder is co-morbid with many psychiatric disorders, among which obsessive-compulsive disorder is the most common. Methods: During a one-year period, 30 patients with Tourette disorder were studied at an adolescent psychiatry referral clinic. It was an analytical-descriptive study. Subjects were selected by convenie...

Gilles de la Tourette syndrome is a childhood-onset syndrome characterized by the presence and persistence of motor and vocal tics. A dysfunction of cortico-striato-pallido-thalamo-cortical networks in this syndrome has been supported by convergent data from neuro-pathological, electrophysiological as well as structural and functional neuroimaging studies. Here, we addressed the question of str...

AIM To evaluate the relationship between diagnosis and clinical course of Tourette syndrome and group A Streptococcus (GAS). METHOD GAS infections, anti-streptococcal, and anti-basal ganglia antibodies (ABGA) were compared between 168 patients (136 males, 32 females) with Tourette syndrome; (median [range] age [25th-75th centile] 10y [8-11y]); median Tourette syndrome duration (25th-75th cent...

Tourette syndrome is a common childhood-onset neuropsychiatric disorder characterized by chronic tics and frequent comorbid conditions such as attention deficit disorder. Most currently used tic-suppressing drugs are frequently associated with serious adverse events. Thus, alternative therapeutic agents with more favorable side-effect profiles are being evaluated. New hypotheses and recent stud...

objectives: tourette syndrome is a disease with vocal and motor tics. this disorder is co-morbid with many psychiatric disorders, among which obsessive-compulsive disorder is the most common. methods: during a one-year period, 30 patients with tourette disorder were studied at an adolescent psychiatry referral clinic. it was an analytical-descriptive study. subjects were selected by convenience...

Tourette syndrome is a neuropsychiatric condition characterized by both motor and phonic tics over a period of at least 1 year with the onset in childhood or adolescence. Apart from the tics, most of the patients with Tourette syndrome have associated neuropsychiatric comorbidities consisting of attention deficit hyperactivity disorder, obsessive compulsive disorder, rage attacks, sleep issues,...

Last version received on 11/8/2000. Approved on 21/8/2000. This work has been supported by the following USPHS grants: MH-70009, MH-30929, MH-49351, HD-03008, MO1-RR-06022 and by a grant from the Tourette Syndrome Association. Inexistent conflict of interests. Contemporary approaches to the treatment of tics in Tourette syndrome Abordagem contemporânea para o tratamento de tiques na síndrome de...