Fingertip units have been proposed as a tool to standardize topical therapy with semisolid formulations. However, no studies to date have characterized the variability in dosing by patients using this concept and whether this variability ultimately affects the topical absorption of drugs. This work aimed to answer these two questions. A first study determined the dose measured, the area of spre...

The introduction of cortisone and hy­ drocortisone with their attendant success in ocular therapy has inevitably sparked a search for better analogs of these steroids. The chief aim of these investigations is the development of a compound that has the maximal curative power and minimal ability to produce undesirable side effects. A host of compounds has been produced during this hunt. The lates...

Hypergranulation tissue (or also known as overgranulation) may negatively influence burn wound healing time and contribute to recurrence of contractures in burn wounds and grafts. Subsequently, the treatment of hypergranulation tissue remains controversial and problematic. In this case series, we aimed to examine the feasibility and document the use of topical hydrocortisone in the treatment of...

counter (OTC) product. After debate the case against won the day by 34 to 31 votes. A narrow margin, but it was an impressive victory; before the debate all the dermatologists that I questioned had said that licensing hydrocortisone as an OTC product was "probably all right." Several pharmaceutical companies are keen to introduce 1% hydrocortisone as a topical product for sale to the public wit...

Topical corticosteroids (TCs) have been the mainstay of treatment in eczematous and inflammatory skin diseases since the introduction of hydrocortisone in 1952. 1 TCs should not be used on the face except for acute inflammatory conditions and that too with caution and for not more than one month. 2 When used appropriately and in safe hands, it is of immense benefit with insignificant side effec...

(Figure 2B). All specimens tested negative for microorganismsbyGrocott-Gomorimethenamine silver andacid-fast bacilli stains andwere not consistentwith lichen sclerosus or lichen simplex chronicus. Hydroxychloroquine therapy had previously failed for this patient, and she was therefore prescribed mycophenolate (500 mg, twice a day) by her pulmonologist. In addition, we recommended 3-times-daily ...

Peristomal skin complications interfere with stoma appliance use and negatively affect patient quality of life. To find an alternative to long-term peristomal skin treatment involving corticosteroid products, a prospective study was conducted to compare the effect of a German chamomile solution to topical steroids on peristomal skin lesions in colostomy patients. Persons seeking care for the t...