Periodontic-orthodontic interactions are mutually beneficial. Combined periodontic and orthodontic treatment can greatly enhance periodontal health and dentofacial esthetics. Adjunctive orthodontic management of pathological tooth migration has unique effects in subjects with moderate to advanced periodontitis. Orthodontic treatment should only be undertaken with healthy periodontium or healthy...

The periodontal therapy of severely damaged teeth that have advanced bone loss, a significant degree of mobility, and often tooth migration and elongation, frequently exposes the dental clinician to difficult decisions regarding the appropriate therapy for the patient. Extensive rehabilitation, with the replacement of periodontally hopeless teeth, has biologic, prognostic, and financial limitat...

The electron microprobe was used to study tooth discoloration caused by old silver amalgam fillings. Oscilloscopic displays were obtained for the distribution of tin, silver, and mercury. In addition, a linear graphic display technic on the Enhancitron was used. The oscilloscopic displays showed the migration of tin from the amalgam into the enamel and dentin as opposed to silver or mercury, or...

Examination and comparison of the morphological features of tooth crown in archaeological and recent samples can be difficult due to the different levels of tooth wear seen both within and between populations. These differences make the comparison of frequency data for Carabelli trait problematic. The aim of the present study is to detect the frequency and degree of expression of Carabelli's tr...

Although it is challenging, the early diagnosis of a vertical root fracture (VRF) is crucial in order to ensure tooth preservation. The purpose of this clinical case report was to describe reparative surgery performed to treat a tooth affected by an incomplete VRF. A 26 year old male patient was suspected to have a VRF in a maxillary left central incisor, and an exploratory flap was performed i...

Abstract Ever since the discovery of Indus valley civilization, scholars have debated linguistic identities its people. This study analyzes numerous archaeological, linguistic, archaeogenetic and historical evidences to claim that words used for elephant (like, ‘pīri’, ‘pīru’) in Bronze Age Mesopotamia, elephant-word Hurrian part an Amarna letter ca. 1400 BC, ivory-word (‘pîruš’) recorded certa...

High mobility group box protein-1 (HMGB1) is mainly recognized as a chemoattractant for macrophages in the initial phase of host response to pathogenic stimuli. However, recent findings provide evidence for anabolic properties in terms of enhanced proliferation, migration, and support of wound healing capacity of mesenchymal cells suggesting a dual role of the cytokine in the regulation of immu...

A 41-year-old man had a significant loss of bone and supporting tissues with pathologic migration of several teeth and several missing teeth. He was treated with an interdisciplinary therapeutic protocol that included nonsurgical periodontal therapy based on strict control of supragingival plaque, subgingival periodontal therapy, orthodontic and endodontic treatment, and replacement of restorat...

Stem cell migration is a critical step during the repair of damaged tissues. In order to achieve appropriate cell-based therapies for tooth and periodontal ligament repair it is necessary first to understand the dynamics of tissue-specific stem cell populations such as dental pulp stem cells (DPSC) and dental follicle stem cells (DFSC). Using time-lapse imaging, we analysed migratory and prolif...

BACKGROUND AND OBJECTIVE The junctional epithelium attaches to the enamel surface with hemidesmosomes (of which laminin-5 and integrin-alpha(6)beta(4) are the main components) in the internal basal lamina. Laminin-5 is also involved in cell motility with integrin-alpha(3)beta(1), although their functions have not yet been clarified.The purpose of this study was to determine the functions of tho...