AIM Longitudinal assessment of clinical and neurophysiological abnormalities in childhood and adolescence and incidence analysis of tandem Charcot-Marie-Tooth disease type 1A gene duplication in Croatian children with Charcot-Marie-Tooth type 1 neuropathy. METHODS Eight Croatian children with Charcot-Marie-Tooth type 1 neuropathy, aged 4-19 years, were studied clinically, neurophysiologically...

Ever since the Chernobyl accident in 1986, that contaminated vast areas in surrounding countries with radiation, abnormalities and birth defects have been reported in human populations. Recently, several studies suggested that the elevated frequency of such abnormalities can be attributed to poverty and stress in affected human populations. Here, we present long-term results for a free-living p...

A case of a 9-year-old child with hereditary gingival fibromatosis, supernumerary tooth, chest deformities, auricular cartilage deformation, joint laxity and undescended testes is described. The exact mode of inheritance is unclear; a new mutation pattern is possible. These features resemble but differ from the previously reported Laband syndrome. The dental treatment consisted of surgical remo...

This report describes a case of combined dental development abnormalities. A patient with a previous ectopically erupted supernumerary maxillary canine presented a new ectopically erupted supernumerary premaxillary tooth with dens invaginatus (Oehlers' type 2) and an aberrant coronal morphology, including a pit in the distal portion of the palatal surface. This tooth would have been diagnosed e...

Background Dental abnormalities are considered important, since they cause aesthetic and functional problems for people. Orthodontic treatment becomes more complicated when craniofacial accompanied with dental abnormalities. Objective This study aims to compare the frequency type of among patients different skeletal malocclusion classes in northern Iran terms age gender. Methods Participants we...

The Witkop syndrome is a rare autosomal dominant disorder characterized by the absence of several teeth and abnormalities of the nails. This is the first report of a rare genetic tooth and nail syndrome diagnosed in a 2.5-year-old boy with early exfoliation of the primary canine, absence of the primary incisors, and nail dysplasia. A homozygous mutation was identified in 3’-UTR of MSX1 gene in ...

incontinentia pigmenti (ip) is a rare x-linked dominant disorder with skin, eye, central nervous system (cns) and tooth abnormalities. according to the reported cases, it is estimated that there have been nearly 900-1200 affected individuals. in this article, the literature is reviewed and a case of ip with characteristic skin lesions and optic atrophy is presented.