Summary An alternative splicing isoform switch is where a pair of transcript isoforms reverse their relative expression abundances in response to external or internal stimuli. Although computational methods are available to study differential alternative splicing, few tools for detection of isoform switches exist and these are based on pairwise comparisons. Here, we provide the TSIS R package, ...

Radio Frequency Micro-Electro-Mechanical-Systems (RF MEMS) based switches are expected to play a key role in the field of microwave switching. Traits like low-loss performance; zero-power consumption and very low inter-modulation distortion have made these switches well suitable for high-performance microwave and millimeter-wave circuits. The design of RF MEMS switches, however, require sophist...

This paper presents an analysis of output queued cell switches which are introduced with generic non-uniformly distributed traffic. Random arbitration is employed whereby non-empty queues compete equally for service within each switching interval. In particular, we study the case of two-state Markov-modulated arrivals in which input ports generate bursty streams that are non-uniformly distribut...

Molecular techniques now allow the design of precise genetic modifications in the mouse. Not only can defined nucleotide changes be engineered into the genome of the mouse, but genetic switches can be designed to target expression or ablation of any gene (for which basic molecular information is available) to any tissue at any defined time. These strategies promise to contribute substantially t...

is the ability to fabricate a large number of small devices economically. However such devices tend to have errors caused by the variations of fabrication and inherent noise signals such as Brownian motion or Johnson noise. This paper advances the understanding of Micro Switch Group Sensors (MSGS). In this paper, a MSGS comprising of 20 switches has been built using electronic circuits and test...

In this paper, a boost converter with a clamp circuit is proposed for high intensity discharge (HID) lamp application. The clamp circuit provides zero voltage turn on for both main and clamp switches. Compared to conventional boost converters, the proposed converter has the following advantages: (i) high voltage gain without suffering from extreme duty ratio, (ii) low stress on the switches and...

in this paper, a new cascaded multilevel inverter by capability of increasing the number of output voltage levels with reduced number of power switches is proposed. the proposed topology consists of series connection of a number of proposed basic multilevel units. in order to generate all voltage levels at the output, five different algorithms are proposed to determine the magnitude of dc volta...

People with motor impairments often face difficulties in accessing interactive applications and services. This paper presents a tool, named FastScanner that enables motor-impaired users to work with any application running in Microsoft Windows, without the need of a posteriori modification, through the use of binary switches as an alternative to traditional input devices. Evaluation of the tool...

The growth of IEC61850-9-2 process bus as a high data rate communication network have a great improved the capability of substation automation system (SAS). This paper discuss a modelling concept of intelligent electronic devices (IED) using OPNET modeller simulation tool. Simulation tool provides a comprehensive development environment for the specification modelling, system simulation and als...