objectives : squamous cell carcinoma (scc) is the most common malignant neoplasm of the oral cavity and a public health threat. tumor progression is believed to be influenced by angiogenesis as well as tumor cell proliferation; however, the correlation of these two factors in tongue scc still remains unclear. this study aimed to assess the correlation of these two factors in tongue scc. materia...

Primary malignant melanoma of the oral cavity is a rare neoplasm, especially on the tongue. We report a case of mucosal melanoma at the base of the tongue, an extremely rare location (only about 30 cases have been reported in literature). The extension study doesn´t revealed distant metastatic lesions. The patient was treated by subtotal glossectomy and bilateral functional neck dissection. Ton...

background: since the earliest days of medicine, the tongue has been considered a good reflection of systemic disease. hip­pocrates, galen and others considered the tongue to be barometer of health. in addition, the early diagnose of tongue le­sions help to recognize the some systemic diseases. the purpose of this study was to determine the frequency of different mor­phological variations (anom...

granular cell tumor is a rare benign neoplasm most commonly appears in the head and neck region, especially in the tongue, cheek mucosa, and palate. occurrence in limbs is even rarer. these tumors account for approximately 0.5% of all soft tissue tumors. granular cell tumor can also affect other organs including skin, breast, and lungs. local recurrence and metastasis is potentially higher in m...

Congenital tumors of the oral cavity are not common.Teratoids are the most common tumors, and in rare cases are associated with cleft soft palate. In this paper a rare case of Epignathus with cleft soft palate, bifida tongue, jaw malocclusion, tongue lipoma, Hypertelorism and low-set ears has been presented. A female infant with a large mass covered with skin and hair arising from hard palate, ...

Myoepithelioma is a rare neoplasm of the salivary glands, generally occurring in the parotid gland and less often in the minor accessory salivary gland of the oral cavity. The histological appearance includes solid, myxoid and reticular growth patterns. Vimentin and S-100 protein are very sensitive but non-specific immunohistochemical markers of neoplastic myoepithelium. Conservative surgery is...

Solitary fibrous tumour (SFT) is a rare, spindle-cell, mesenchymal neoplasm with haemangiopericytoma-like branching vascular pattern. The tumour has been reported in various locations but the oral cavity is a distinctly uncommon region. We describe a case of solitary fibrous tumour (SFT) in the tongue of a 15-year-old girl. Microscopically it had features characteristic for SFT and a common imm...

Granular cell tumors are uncommon soft tissue neoplasm of nerve sheath origin, which are predominately benign. Granular cells can be found at any site in the body including the tongue, skin, subcutaneous tissue, breast, gastrointestinal, and urogenital systems. However, granular cell tumors have only been rarely described in the chest wall. Here we report a case of a granular cell tumor that oc...

BACKGROUND The cancer which appears in the mobile portion of the tongue is the most common neoplasm of the oral cavity. The objective of this study was to analyse oral tongue cancer epidemiology in a population of 610 patients diagnosed between 1990 and 2008 and detailed in the Tumour Registry of the Madrid region. MATERIAL AND METHODS A retrospective analysis based on the following variables...

Granular cell tumor (GCT) is a relatively uncommon lesion occurring in almost any part of the body, including the orofacial region. The tongue and the buccal mucosa are common intra oral sites. Although aggressive and malignant variants of this neoplasm have been described, most GCTs are benign. The histogenesis of the lesion still remains unknown. However, histochemical and ultra-structural st...