نتایج جستجو برای: toll like

تعداد نتایج: 658351  

Journal: :hepatitis monthly 0
yizhong wang department of infectious diseases, shanghai children’s hospital, shanghai jiao tong university, shanghai, china jieliang li department of pathology and laboratory medicine, school of medicine, temple university, philadelphia, usa xu wang department of pathology and laboratory medicine, school of medicine, temple university, philadelphia, usa yu zhou department of pathology and laboratory medicine, school of medicine, temple university, philadelphia, usa ting zhang department of infectious diseases, shanghai children’s hospital, shanghai jiao tong university, shanghai, china; department of pathology and laboratory medicine, school of medicine, temple university, philadelphia, usa. tel: +1-2157072370, e-mail:; ting zhang, department of infectious diseases, shanghai children’s hospital, shanghai jiao tong university, shanghai, china. tel: +86-2152976331 wenzhe ho department of pathology and laboratory medicine, school of medicine, temple university, philadelphia, usa; department of pathology and laboratory medicine, school of medicine, temple university, philadelphia, usa. tel: +1-2157072370, e-mail:; ting zhang, department of infectious diseases, shanghai children’s hospital, shanghai jiao tong university, shanghai, china. tel: +86-2152976331

background macrophages play critical roles in innate immune response in the liver. whether macrophages participate in liver innate immunity against hcv replication is poorly understood objectives the aim of this study was to investigate the role of macrophages in liver innate immunity against hcv replication. conclusions macrophages may play an important role in liver innate immunity against hc...

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Journal: :reports of biochemistry and molecular biology 0
mohammad reza khakzad tel: +98 9151176352; fax: +98 5112250048 ahmad saffari internal medicine department, mashhad branch, aria hospital, islamic azad university, mashhad, iran niloofar mohamadpour department of microbiology, mashhad branch, islamic azad university, mashhad, iran mojtaba sankian immunobiochemistry lab, immunology research center, mashhad university of medical sciences, mashhad, iran abdolreza varasteh allergy research center, mashhad university of medical sciences, mashhad, iran farhad salari immunobiochemistry lab, immunology research center, mashhad university of medical sciences, mashhad, iran

background: it is not yet known which types of toll-like receptors (tlrs) are most effective in helicobacter pylori (h. pylori) recognition. it is also not known which gastric zones have the most prominent roles in tlr-mediated bacterial recognition. the aim of this work was to analyze the expression of tlr2 and tlr4 in biopsy specimens from h. pylori-infected patients. methods: thirty-eight pa...

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ژورنال: مجله دانشگاه علوم پزشکی فسا 2015
Karimi, Mohammad Hossein, Moazeni, Seyed Mohamad, Mokhtariazad, Talat, shariat, Afsson, Yaghobi, Ramin,

Background & Objectives: Interaction of cytomegalovirus glycoprotein B with toll-like receptors of dendritic cells leads to early signaling and innate immune responses. The aim of this study is to evaluate the effects of cytomegalovirus glycoprotein B on the maturation and function of monocyte-derived dendritic cells in treated groups in comparison with control groups. Materials & Methods: Bloo...

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Journal: :iranian journal of allergy, asthma and immunology 0
sahar mortezagholi department of immunology, school of medicine, tabriz university of medical sciences, tabriz, iran. zohreh babaloo department of immunology, school of medicine, tabriz university of medical sciences, tabriz, iran parisa rahimzadeh department of immunology, school of public health, tehran university of medical sciences, tehran, iran mojgan ghaedi department of immunology, school of public health, tehran university of medical sciences, tehran, iran hayedeh namdari department of immunology, school of medicine, shiraz university of medical sciences, shiraz, iran shirin assar rheumatology research center, tehran university of medical sciences, tehran, iran

systemic lupus erythematosus (sle) is a chronic autoimmune disease which results in damage to various organs. some animal studies have revealed that activation of toll-like receptors (tlrs) is important in the pathogenesis of sle. in the present study, the percentage of different immune cell subsets in 35 sle patients and 38 control subjects was analyzed by flow cytometry. we also assessed the ...

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Journal: :iranian biomedical journal 0
leila sadat-hatamnezhad asghar tanomand javad mahmoudi siamak sandoghchian shotorbani

background: stroke is a leading cause of death all around the world, and ischemic stroke is considered to be the most common stroke type. toll-like receptors (tlrs) are important molecules for detection of both pathogen invasion and tissue damage. in this regard, the purpose of this study was to assess the expression level of tlr2 on monocytes in patients with ischemic stroke and to evaluate th...

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Journal: :avicenna journal of medical biotechnology 0

the role of microbiota in health and disease is the subject of rigorous investigation. several studies have demonstrated that microbiota and the pattern-recognition receptors contribute to intestinal tumourigenesis; the exact mechanism of which is still obscure. myd88 is the downstream effector of all toll-like receptors (tlrs) except tlr3. however, the alternative myd88-independent pathway is ...

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Journal: :iranian journal of allergy, asthma and immunology 0
qian zhang department of respiratory medicine, affiliated changzhou no.2 people’s hospital, nanjing medical university, changzhou, china and department of respiratory medicine, nanjing general hospital of nanjing military command, nanjing, china fen-hong qian department of respiratory medicine, affiliated jiangbing hospital, jiangsu university, zhenjiang, china xiao-wei yin department of respiratory medicine, affiliated changzhou no.2 people’s hospital, nanjing medical university, changzhou, china qi cao department of respiratory medicine, affiliated changzhou no.2 people’s hospital, nanjing medical university, changzhou, china jian-ling bai department of epidemiology and biostatistics, school of public health, nanjing medical university, nanjing, china qiang du department of respiratory medicine, second affiliated hospital, nanjing medical university, nanjing , china

toll-like receptor (tlr) 7 and 8 mediate anti-virus immunity and are of particular relevance to asthma. however, very little information about genetic association on tlr7/8 and asthma are available. this study aimed to evaluate the effects of polymorphisms in tlr7 and 8 on asthma risk and asthma-related phenotypes in a chinese han population. we enrolled 462 unrelated adult asthmatic patients a...

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Journal: :reports of biochemistry and molecular biology 0
mohsen tehrani immunobiochemistry lab, immunology research center, bu-ali research institute, mashhad, iran abdol-reza varasteh immunobiochemistry lab, immunology research center, bu-ali research institute, mashhad, iran mohammad reza khakzad zakaria research center, azad university of mashhad, mashhad, iran majid mirsadraee zakaria research center, azad university of mashhad, mashhad, iran mojtaba sankian tel: +98 511-7112410; fax: + 98 511- 7112616

background: recently, reports have indicated a role for the membrane form of toll-like receptor 2 (tlr2) in asthma pathogenesis. in this study we examined soluble tlr2 levels in serum and sputum of asthmatic and healthy subjects. methods: serum and sputum samples were obtained from 33 asthmatic and 19 healthy subjects. the asthmatics were classified into four groups according to the global init...

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Journal: :journal of medical microbiology and infectious diseases 0
mehri habibi department of molecular biology, pasteur institute of iran, tehran, iran mohammad reza asadi karam department of molecular biology, pasteur institute of iran, tehran, iran saeid bouzari department of molecular biology, pasteur institute of iran, tehran, iran

introduction : the innate immune system as the first line of defense against the pathogens recognizes pathogen-associated molecular patterns (pamps) by toll-like receptors (tlrs). interaction of bacterial pamps by tlrs results in activation of innate and acquired immunity. fimh adhesin, a minor component of type 1 fimbriae encoded by uropathogenic escherichia coli (upec) is a pamp of tlr4 that ...

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Journal: :iranian journal of parasitology 0
hassan borji dept. of pathobiology, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran alireza haghparast dept. of pathobiology, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran nooshinmehr soleimani dept. of pathobiology, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran mohammad azizzadeh dept. of clinical science, school of veterinary medicine, ferdowsi university of mashhad, mashhad, iran mohammad hossein nazemshirazi central laboratories of khorasan razavi veterinary organization, mashhad, iran

background: recognition of helminth-derived pathogen associated molecular patterns (pamps) by pattern recognition receptors (prrs), including toll like recep­tors (tlrs) is the first step towards initiating anti–helminth immune re­sponses. methods : using somatic antigens of ostertagia occidentalis, an important abomasal parasite of ruminants, the expression of ovine tlr2 and tlr4 in peripheral...

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