نتایج جستجو برای: tlr algorithm

تعداد نتایج: 762507  

Aflatoonian R, Aghajanpour S Koruji M, Lakpour MR, Rajabian Naghandar M Sabbaghian M Sadighi Gilani MA Shahverdi AH

Background: Toll-like receptors (TLRs) constitute a major part of innate immunity, which can distinguish pathogen associate molecular pattern. Sertoli cells create a special immunological niche that protects somniferous tubules from auto antigens and pathogens. These cells are the only somatic cells in somniferous that protect testis cells against pathogens. The purpose of this study was to eva...

Journal: :iranian journal of immunology 0
afsoon shariat department of biology, college of basic sciences, tehran science and research branch, islamic azad university, tehran mohammad hossein karimi shiraz transplant research center, namazi hospital, shiraz university of medical sciences, shiraz talat mokhtariazad department of virology, school of public health, tehran university of medical sciences, seyed mohammad moazzeni department of immunology, faculty of medical sciences, tarbiat modarres university, tehran bita geramizadeh shiraz transplant research center, namazi hospital, shiraz university of medical sciences, shiraz seyed ali malekhosseini shiraz transplant center, namazi hospital, shiraz university of medical sciences, shiraz, iran ramin yaghobi

background: dendritic cells (dcs) are potent antigen presenting cells for triggering of the immune reaction post transplantation. these cells are centrally involved in the initiation of t cell-dependent immune responses. objective: to compare the level of dc maturation and function in liver transplant recipients with healthy controls. methods: in this study, twelve peripheral blood samples were...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بیرجند - دانشکده کشاورزی 1390

tlr ها گروهی قدیمی از ژن ها هستند که در مهره داران و بی مهرگان یافت شده اند و این گیرنده ها در گیاهان نیز یافت می شوند. در پستانداران اعضای خانواده ژنtlr نقش عمده ای را در شناخت خصوصیات مولکولی مرتبط با پاتوژن ها در پروتیین های باکتری ها ویروس ها قارج ها و پروتوزآ ایفا می کنند tlrها شامل دامنه وسیعی از گیرنده ها هستند که مسئول باند شدن باpamp ( الگوی القا کننده پاتوژن که با گیرنده های سلول های ...

پایان نامه :دانشگاه آزاد اسلامی واحد تهران شرق - دانشکده علوم پایه 1393

به طور معمول مازاد تغذیه، در بدن به صورت چربی ذخیره و به چاقی منجر می شود. یکی از عوامل ابتلا به دیابت نوع 2 ، چاقی است. tlr به عنوان یک پیوند ملکولی بین اسید های چرب آزاد ، التهاب و سیستم ایمنی عمل می کنند. tlr از طریق تولید سایتوکاین های پایین دست از قبیل il-10, il-6 ،il-1? ، tnf-? منجر به بروز التهاب می شوند. این سایتوکاین ها در پاسخ به محرک التهابی ترشح می شوند و مسیر های سیگنالینگ التهاب...

Abolfazl Gholipour Ghorbanali Rahimian Hedayatollah Shirzad, Nader Bagheri

Background & Aims: Helicobacter pylori (H. pylori) infection is associated with peptic ulcer and gastric cancer. Polymorphisms of the genes coding Toll-like receptors (TLRs) may influence the innate and adaptive immune responses and affect the susceptibility to H. pylori or the disease outcomes. But the details and association to different polymorphis...

Journal: :Cell Death & Differentiation 2006

Journal: :cell journal 0
zahra zandieh fatemehsadat amjadi mahnaz ashrafi abbas aflatoonian alireza fazeli reza aflatoonian

background: toll like receptors (tlrs) are one of the main components of the innate immune system. it has been reported that expression of these receptors are altered in the female reproductive tract (frt) during menstrual cycle. here we used a fallopian tube epithelial cell line (oe-e6/e7) to evaluate the effect of two sex hormones in modulating tlr expression. materials and methods: in this e...

Journal: :In vivo 2016
Nazan Atalan Hande Karagedik Leyla Acar Selim Isbir Seda Gulec Yilmaz Arzu Ergen Turgay Isbir

AIM To analyze the effect of TLR-9 (-1486 T>C) and TLR-9 (C>T) gene polymorphisms both at TLR-9 levels and together with their sepsis parameters. In this regard, the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique was used in order to detect TLR-9 gene polymorphisms, whereas the ELISA technique was used to analyze TLR-9 serum levels in 80 sepsis patients ...

2011
Arindam Maitra Jayashree Shanker Debabrata Dash Prathima Arvind Vijay V. Kakkar

INTRODUCTION Toll-like receptors (TLRs) are an important link between innate and adaptive immunity. MATERIAL AND METHODS Expression of TLR-2, TLR-4, and TLR-9 genes was assessed in 60 coronary artery disease (CAD) patients and 79 controls by SYBR Green 1 based real time PCR assay. RESULTS Expression of the TLR-2 gene was found to be significantly elevated in cases (1.295 ±0.09) compared to ...

Journal: :Journal of Experimental Medicine 2009

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