Material surface is a key determinant of host response on implanted biomaterial. Therefore, modification of the implant surface may optimize implant-tissue reactions. Inflammatory reaction is inevitable after biomaterial implantation, but prolonged inflammation may lead to adverse reactions and subsequent implant failure. Proinflammatory activities of cytokines like interleukin (IL)-1, IL-6, an...

Recent advances in abrasive waterjet (AWJ) technology have resulted in new processes for surface treatment that are capable of introducing compressive residual stresses with simultaneous changes in the surface texture. While the surface residual stress resulting from AWJ peening has been examined, the subsurface residual stress field resulting from this process has not been evaluated. In the pr...

The purpose of this paper is to optimize the EDM parameters to get the better surface finish on the Titanium alloys Ti6AL4V. The continuous advancement of the alloy is fulfilling the demand of the industry but for advance material like Titanium alloys Ti6AL4V partially adopted by industries cause of the difficulties in machining. Non Conventional machining process like Spark Erosion Electrical ...

C. Rontescu, T. D. Cicic, C. G. Amza, O. Chivu, Polytechnic University of Bucharest, Romania. D. Dobrotă, Engineering Faculty, University “Constantin Brâncuşi” of Târgu-Jiu, România This paper presents the results obtained following the Finite Element Method (FEM) simulations on a bike frame made of 3 different materials, Al6061, Carbon Fiber and Ti6Al4V, in order to identify the optimum materi...

Infections are a devastating complication of titanium alloy orthopedic implants. Current therapies include antibiotic-impregnated bone cement and antibiotic-containing coatings. Daptomycin (DAP) (1) is a novel peptide antibiotic that penetrates the cell membranes of Gram-positive bacteria. Few DAP-resistant strains have appeared so far. We hypothesized that when DAP covalently bonded via a flex...

Water Droplet Erosion (WDE) as a material degradation phenomenon has been a concern in power generation industries for decades. Steam turbine blades and the compressor blades of gas turbines that use water injection usually suffer from WDE. The present work focuses on studying erosion resistance of TiAl as a potential alloy for turbine blades compared to Ti6Al4V, a frequently used blade alloy. ...

The aim of this work was to prepare hydroxyapatite coatings (HAp) by a sol-gel method on Ti6Al4V alloy and to study the bioactivity, biocompatibility and corrosion protection behaviour of these coatings in presence of simulated body fluids (SBFs). Thermogravimetric/Differential Thermal Analyses (TG/DTA) and X-ray Diffraction (XRD) have been applied to obtain information about the phase transfor...

Osteoconductive mineral coatings are beneficial for improving the osteointegration of metallic orthopedic/dental implants, but achieving adequate structural integration between the surface minerals and underlying metallic substrates has been a significant challenge. Here, we report covalent grafting of zwitterionic poly(sulfobetaine methacrylate) (pSBMA) brushes on the Ti6Al4V substrates to pro...

In an effort to examine the effect of the microstructural changes of the Ti6Al4V alloy, two heat treatments were carried out below (Ti6Al4V800) and above (Ti6Al4V1050) its β-phase transformation temperature. After each treatment, globular and lamellar microstructures were obtained. Saos-2 pre-osteoblast human osteosarcoma cells were seeded onto Ti6Al4V alloy disks and immersed in cell culture f...

Two heat treatments were carried out below (Ti6Al4V800) and above (Ti6Al4V1050) Ti6Al4V beta-phase transformation temperature (980 °C), with the purpose of studying the effect of microstructure on the adhesion and proliferation of fibroblast cells, as well as their electrochemical behavior. These alloys were seeded with 10,000 L929 fibroblast cells and immersed for 7 days in the cell culture at...