We report herein a case of hyperthyroid Graves' disease developed from asymptomatic autoimmune thyroiditis (AAT). A 25-year-old single female with AAT was followed up for over 3 years. Thereafter her condition progressed to hyperthyroidism with both positive TSH receptor antibodies (TRAb) and an increase in antithyroidal antibodies. It is possible that there was continuous destruction of thyroi...

BACKGROUND The development of antibodies to thyroid peroxidase, thyroglobulin, and thyroid-stimulating hormone (TSH) receptor is a main feature of autoimmune thyroid diseases. OBJECTIVE To investigate whether complete removal of thyroid antigens results in the abatement of humoral thyroid autoimmunity. DESIGN Retrospective chart review study of patients treated and monitored with a standard...

Received 7/19/2002; accepted 8/7/2002. For correspondence or reprints contact: Yu-Wen Chen M.D., Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Koahsiung, 100 ShihChuan 1st Road, Kaohsiung 807, Taiwan. Tel: (886)7-3121101 ext. 7153, Fax: (886) 7-3117521, E-mail: [email protected] Chronic autoimmune thyroiditis is the major cause of hypothyroidism for young children; howeve...

INTRODUCTION The presentation, diagnosis, clinical course and treatment of a man with hyperthyroidism secondary to autoimmune thyroiditis in the setting of type 1 diabetes mellitus has not previously been described. CASE PRESENTATION A 32-year-old European-American man with an eight-year history of type 1 diabetes mellitus presented with an unintentional 22-pound weight loss but an otherwise ...

AIMS To compare the prevalence of thyroid peroxidase antibodies in 25 children with autoimmune thyroid disorders and in 41 children and young adults with type 1 diabetes, and to test the prevalence of thyrotropin receptor antibodies. METHODS Two commercially available radioimmunoassays for antibodies to thyroid peroxidase, a commercially available agglutination test of particles coated with t...

Autoimmune thyroiditis is one of the most common causes acquired hypothyroidism in children and adolescents. Both genetic susceptibility environmental factors play a role etiopathogenesis. We report two cases autoimmune here with varied presentation. them had different clinical features at On investigation, both elevated thyroid-stimulating hormone (TSH), low T4 anti-Thyroid peroxidase (TPO) an...

Abstract Multiple susceptibility genes can be involved in the development of Hashimoto’s thyroiditis. Some these are implicated other autoimmune diseases, while others specific to thyroid response. 153 patients with pathology were enrolled study (152 women and 1 man, average age was 46,02±14,3). They divided into 3 groups: 16 postoperative hypothyroidism; 65 hypothyroidism resulting from thyroi...

OBJECTIVE To characterize a cohort of patients with type 1 diabetes mellitus (T1DM) on the presence of other autoimmune disorders that could establish the diagnosis of autoimmune polyglandular syndrome (APS). SUBJECTS AND METHODS We included 151 patients with T1DM. The following clinical parameters were analyzed: gender, current age, disease duration, previous history of autoimmune disorders,...

UNLABELLED Acquired cerebellar ataxia has been described with hypothyroidism, and is typically reversible by thyroid hormone replacement therapy. The cerebellar dysfunction has been attributed to metabolic and physiological effects of the endocrine disorder. In a few patients, however, ataxia has persisted despite thyroid replacement therapy. Other mechanisms may be involved in ataxia associate...