BACKGROUND Marine-Lenhart syndrome is defined as the co-occurrence of Graves' disease and functional nodules. The vast majority of autonomous adenomas are benign, whereas functional thyroid carcinomas are considered to be rare. Here, we describe a case of simultaneous occurrence of Marine-Lenhart syndrome and a papillary microcarcinoma embedded in a functional nodule. CASE PRESENTATION A 55 y...

INTRODUCTION We aimed to retrospectively assess the prevalence of microcarcinoma in thyroidectomy specimens from a Greek population and the role of histopathology in determining management of these patients. METHODS We used histopathological reports of thyroidectomies performed in a Greek general district hospital. The samples consisted of 191 thyroidectomies performed between January 1997 an...

PURPOSE With the increasing incidence of papillary thyroid microcarcinoma (PTMC), familial papillary thyroid microcarcinoma (FPTMC) is now recognized more frequently. However, the biological behavior of FPTMC is poorly understood. The aim of this study was to investigate the prevalence of FPTMC and its biological aggressiveness. METHODS Between March 2006 and July 2010, 2,414 patients underwe...

INTRODUCTION Endogenous thyroid-stimulating hormone-stimulated thyroglobulin collected after total thyroidectomy is a useful predictor of better prognosis in patients with differentiated thyroid carcinomas in general, but studies with microcarcinomas are scarce. OBJECTIVE To assess whether the first postoperative stimulated thyroglobulin measurement is a prognostic factor in patients with mic...

Mature fat tissue can be found in both benign lesions and neoplasms of the thyroid gland. The pathophysiology of adipose tissue infiltration in the thyroid gland is not clear. Three cases of diffuse lipomatosis and two cases of thyroid papillary microcarcinoma containing mature fat in their stroma were diagnosed between 2002 and 2009 years. These five cases are presented in this report with a r...

Thyroid nodules are clinically palpable in 4-7% of adults in the United States. With ultrasound examination, thyroid nodules are identified in up to 70% of adults. In asymptomatic individuals, the potential for malignancy underlies the clinical importance of investigating thyroid nodules. Increased diagnostic accuracy has improved non-operative management of benign thyroid lesions. Appropriate ...

Aim: The aim of this study is to reveal the value preoperative neutrophil lymphocyte ratio in differential diagnosis between papillary thyroid carcinoma, microcarcinoma and benign multinodular goiter. Materials methods: Patients with microcarcinoma, goiter whose histopathological was confirmed by postoperative pathology reports were included study. Results: TSH levels statistically significantl...

OBJECTIVE Ghrelin plays a role in several processes of cancer progression, and numerous cancer types express ghrelin and its receptor. We aimed to investigate serum levels of ghrelin in patients with papillary thyroid carcinoma (PTC) and its association with the prognostic factors in PTC. MATERIALS AND METHODS We enrolled 54 patients with thyroid cancer (7 male, 47 female) and 24 healthy cont...