Endobronchial metastasis is a rare manifestation of differentiated thyroid cancer. A 79-year-old male was admitted to the hospital with shortness of breath, chest pain, anemia, and weight loss. Computed tomography of chest revealed multiple lung nodules. Bronchoscopy showed an endobronchial lesion in the right upper lobe. The biopsy of the lesion demonstrated neoplastic cells stained positive f...

metastasis to the oral region is very rare and accounts for less than 1% of oral malignant tumors. breast, lung, kidney, adrenal, gastro intestinal tract and prostates are most common primary tumors from which metastasis to oral region occur frequently. metastasis from thyroid gland is extremely rare to oral region. we present an unusual case of metastatic follicular carcinoma of thyroid in max...

With fewer than 40 cases described in the otolaryngology literature, mixed medullary papillary thyroid carcinoma represents a rare but phenotypically distinct tumor. While isolated medullary carcinoma may be admixed with normal follicular structures, true mixed carcinoma displays morphological and immunological characteristics of medullary and papillary carcinoma within a single lesion. We repo...

A 52-year-old man presented with subacute thyroiditis and showed an intensely hypermetabolic thyroid lesion on (18)F-FDG PET/CT. The patient also had coexisting chronic lymphocytic thyroiditis. The lesion of subacute thyroiditis revealed an SUV(max) of 9.1 g/mL and was ill-defined, heterogeneous, markedly hypoechoic, and hypovascular on US. Biopsy demonstrated histologic findings of subacute th...

We describe the case of a 48-year-old woman who presented with a thyroid lesion incidentally detected on positron emission tomography/computed tomography for a suspicious lung lesion. Subsequent clinical examination and investigations revealed a 3 cm nodule in the left lower pole of the thyroid. Fine needle aspiration was indeterminate for malignancy. A left hemithyroidectomy was performed and ...

Primary thyroid T-cell lymphoma is rare, with only 19 cases reported previously. T-cell prolymphocytic leukemia/ lymphoma (T-PLL) is a rare entity among T-cell lymphomas. T-PLL patients present with hepatosplenomegaly, lymphadenopathy, skin infiltration and a high leukocyte count, sometimes with anaemia and thrombocytopenia, but thyroid infiltration has been reported in only one other case. Her...

Thyroid metastases account for approximately 1.4-3% of all malignancies of the thyroid gland. Thyroid metastases are most common in: clarocellular carcinoma of the kidney, lung cancer, breast cancer, malignant melanoma and cancers of gastrointestinal tract. A rare situation is when thyroid metastasis is diagnosed before detecting primary malignant focus and when it is the first manifestation of...

Objective: The purpose of this study is to evaluate the clinicopathologic characteristics and treatment outcomes of Papillary Thyroid Carcinomas (PTC) of the isthmus and to establish an appropriate surgical strategy. Methods: Thirty-four patients with PTC in isthmus are managed by surgery in National Cancer Center/Cancer Hospital of Chinese Academy of Medical Sciences, Peking Union Medical Coll...

Objective: Nodular goiter is the commonest lesion of thyroid gland. This study was carried out to see histopathological pattern of thyroid enlargement. Methodology: All thyroid lesions received in the Department of Pathology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre Karachi, over a period of five years were reviewed and relevant special stains were performed. Results...