Few studies have dealt with thiopental sodium-induced anaesthetic action and the effect of combining meloxicam (a high plasma protein-bound) in 10–15 day old chicks. First, analgesic median effective dose (ED50) was determined as 35.85 mg/kg, IM by up-and-down routine, while hypnotic ED50 value 34.40 chick model. A sodium injection (18, 36 72 IM) produces a significant dose-responsive chicks, b...

BACKGROUND Emergence Agitation (EA) is a common problem in pediatric anesthesia. The current study evaluated the effect of intravenous lidocaine combined with propofol or thiopental sodium to control EA by sevoflurane in children. OBJECTIVES The current study aimed to compare the effectiveness of two anesthesia regimen propofol-lidocaine and thiopental sodium lidocaine to control sevoflurane-...

Rabbits are widely used as laboratory animals for experimental surgery. Anesthesia of rabbits may present complications unless the method is easy to apply and safe to use. In present study, effects of different dosages of vitamin C on thiopental sodium induced anesthesia in 25 male New Zealand white rabbits were studied. In the animals that had not received vitamin C treatment before thiopental...

a general, simple, practical and convenient method has been described for the synthesis of anesthetic drug thiopental using thiourea in the presence of sodium ethoxide. anesthetic drug of thiopental was prepared in two stages; during the first stage, the alkylation of mthyl cyanoacetate was performed which was then to be followed by cyclization. alkylation of methyl cyanoacetate which was perfo...

The methanolic leaf extract of Thuja occidentalis was evaluated for possible sedative activities in mice. Sedative activity was evaluated by using hole cross, open field, thiopental sodium-induced sleeping time and elevated-plus maze (EPM) tests at 200mg/kg and 400 mg/kg.  The extract decreased the locomotor activity of mice in hole cross, open field and EPM test and showed the remarka...

background:   objective: this study aimed at investigating the side effects and hemodynamic effects of using thiopental sodium and propofal as well as effects of these drugs on pregnancy outcome in art cycles.   materials and methods: in this double blinded) randomized controlled trial, 90 woman candidate for art were randomly divided into two groups. 47 patients received propofol (2.5 mg/kg) a...

rabbits are widely used as laboratory animals for experimental surgery. anesthesia of rabbits may present complications unless the method is easy to apply and safe to use. in present study, effects of different dosages of vitamin c on thiopental sodium induced anesthesia in 25 male new zealand white rabbits were studied. in the animals that had not received vitamin c treatment before thiopental...

Background: Pre-anesthetic medication is often required in children to provide anxiolysis and to lessen the psychological impact of hospitalization and procedures. In this study, we compared the effects of intravenous ketamine versus thiopental on the separation anxiety and emergence agitation in children undergoing tonsillectomy/adenoidectomy. Methods: Eighty-two children aged 2-8 years schedu...