Objectives: In the study, it was aimed to determine Thiol/Disulphide profile in patients with relapsed brucellosis and relationship between Ischemia Modified Albumin (IMA) Levels profile. Methods: Native thiol, Total Disulphide, Disulphide/Native Disulphide/Total IMA levels were measured forty healthy control group by using newly developed method this cross-sectional study. Results: There no st...

Cysteine plays an important role in the regulation of redox chemistry and gene expression and is essential in the structural and macromolecular organisation of proteins. Thiol oxidation leads to misfolding and the influencing of the protein function (Buczek et al., 2007). In our experiments, we have identified an oxidised cytoskeletal protein actin involved in the rearrangement of filament in t...

The electrochemical quartz crystal microbalance (EQCM) was used to study the electrosyntheses and electrochemical properties of two kinds of polyaniline (PANI)-thiol composite films in aqueous solutions, which were prepared by covalent binding of a thiol to the oxidized forms of PANI (PANI(post)-thiol, protocol A), and electropolymerization of aniline in the presence of a thiol (PANI(poly)-thio...

BACKGROUND The aim of this study was to investigate a novel oxidative stress marker (thiol/disulphide homeostasis) in patients with acute myocardial infarction (AMI) and compare the results with healthy controls for the first time in literature. METHODS A total of 450 participants including 300 patients with AMI and 150 healthy individuals were included in the study. Left ventricular ejection...

Amaç: Kronik myeloid lösemi (KML), bcr-abl füzyon geninin pozitifliği ile karakterize olan myeloproliferatif bir hastalıktır. Oksidatif stres bu hastalarda DNA hasarına yol açarak hastalığın patogenezinde rol oynuyor olabilir. Thiol molekülleri organizmayı oksidatif stresin zararlı etkilerinden korumaktadır. Biz de çalışmamızda KML hastalarında thiol/disülfit dengesinin durumunu araştırmayı ama...

Objective: In this study, we aimed to evaluate the relationship between thiol-disulfide homoeostasis and hemogram parameters in COVID-19 patients.
 Methods: Total thiol(TT), Native thiol(NT), dynamic disulfide status(DDS), DDS/NT, DDS/TT, NT/TT ratio CBC were analyzed 68 patients with positive 31 healthy individuals.
 Results: TT, NT, DD, hemoglobin hematocrit levels higher control gr...

Backraund; Thiols are important elements for oxidation reactions and under oxidative stress. The aim of this study was to determine thiole levels, an antioxidative marker in CAD patients with stable acute coronary syndrome. Methods; 210 the included were diagnosed syndrome (ACS), 205 consisted angina pectoris (SAP). Thiol groups levels thiol/disulphide homeostasis measured by spectrophotometric...

OBJECTIVES To develop a novel and automated assay determining plasma thiol/disulphide homeostasis, which consists of thiol-disulphide exchanges. DESIGN AND METHODS Native thiol and total thiol concentrations were synchronously measured as a paired test. In the first vessel, the amount of native thiol groups was measured by a modified Ellman reagent. At the parallel run, first, dynamic disulph...