Cooper, K. E. Some historical perspectives on thermoregulation. J Appl Physiol 92: 1717–1724, 2002; 10.1152/japplphysiol.01051.2001.—In this paper, selected historical aspects of thermoregulation and fever are presented as background to the application of molecular biology to thermoregulation. Temperature-sensing mechanisms, coordination of thermal information, thermoregulatory circuitry, effer...