OBJECTIVES Obesity and obesity-associated inflammation is central to a variety of end-organ sequelae including atherosclerosis, a leading cause of death worldwide. Although mouse models have provided important insights into the immunopathogenesis of various diseases, modeling atherosclerosis in mice has proven difficult. Specifically, wild-type (WT) mice are resistant to developing atherosclero...

RATIONALE Prenatal cigarette smoke (CS) exposure, increased environmental temperature, and hypoxic episodes have been postulated as major risk factors for sudden infant death syndrome. OBJECTIVES To test the hypothesis that maternal CS exposure disrupts eupneic breathing and depresses breathing responses of neonatal rats to thermal and hypoxic challenges. METHODS Experiments were performed ...

Rats under thermoneutral conditions and fed mushroom-Se in dietary supplementation showed a significant fold increase (P<0.05) in mRNA expression relative to basal treatment (thermoneutral, control diet) of GPx-1 (2.98±0.82), GPx-2 (1.8±1.4), TrxR-1 (1.83±0.64) and SeP (2.77±0.92). Supplementation with α-tocopherol alone affected the expression of GPx-1 (1.83±0.82) and SeP (2.21±0.92). Rats sub...

The present study aimed to investigate the chronic effects of caudal artery sympathectomy on thermoregulatory adjustments induced by passive heating. Male Wistar rats were subjected to two surgical procedures: caudal artery denervation (CAD) or sham surgery (Sham-CAD) and intraperitoneal implantation of a temperature sensor. On the day of the experiments, the animals were exposed to an ambient ...

To investigate the effects of body temperature decrease which occurred along with cold exposure and menstrual cycle, on color sensation, differential limen (DL) and points of subjectively equality (PSE) or red, green, blue and gray colors were measured by using methods of limit in six young female subjects. also, the subjectively preferred complexion was selected. The lowest value in tympanic m...

The resting metabolic rate (RMR) represents the energy required to sustain normal body functions and homeostasis in an awake individual under ambient thermoneutral conditions during rest [...]

Although the mechanisms remain unknown, maternal core temperature (Tc) decreases near term of pregnancy and is increased throughout lactation in rats. The purpose of our present experiments was to determine whether pregnancy and lactation shift the thermoneutral zone of rats and to investigate whether the changes in maternal Tc during pregnancy and lactation result from "forced" or "regulated" ...