Determining the susceptibility of pathogens to antibacterial substances is one key steps in bacteriological diagnostics that affects success both therapeutic therapy and appropriate selection cosmetic products. Antibiotic chemotherapeutic sensitivity tests determine ability an antimicrobial agent inhibit growth a microorganism vitro.

The identification of cancer preventive or therapeutic substances as well as carcinogenic risk assessment of chemicals is nowadays mostly dependent on animal studies. In vitro cell transformation assays mimic different stages of the in vivo neoplastic process and represent an excellent alternative to study carcinogenesis and therapeutic options. In the BALB/c-3T3 two-stage transformation assay ...

objectives: according to the gateway drug theory, tobacco use is a predisposing factor for future substance abuse. this study was conducted to compare nicotine and opiate dependents to identify the differences between their personality traits and psychopathology that makes them turn to other substances after cigarette smoking. methods: a causal-comparative study was conducted. three groups were...

Ademir dos Santos,* Wander Gustavo Botero, Iramaia Corrêa Bellin, Luciana Camargo de Oliveira, Julio Cesar Rocha, André Gustavo Ribeiro Mendonça and Antonio Francisco Godinho a Instituto de Química, Universidade Estadual de São Paulo, CP 355, 14801-970 Araraquara-SP, Brazil b Centro de Assistência Toxicológica, Instituto de Biociências, Universidade Estadual de São Paulo, CP 520, 18618-000 Botu...

Traditional folk medicine makes good use of the flora and fauna of a region, including a number of mineral substances. These herbs and animals are used either whole or in part and made up in either simple or complicated preparations and have proved to be effective therapeutic remedies. Some of these medicinal substances of animal origin have been quite thoroughly studied with modern scientific ...

background and aims: sea buckthorn (hippophae rhamnoides l.) is a deciduous plant and has highly variable type and size, from small shrubs to medium-sized trees, traditionally growing in tibet and currently all over the world especially in europe and asia. this study aimed to overview some of therapeutic and non-therapeutic properties of sbt and its potential benefits and side effects in order ...

In contrast to the general assumption that polyethyleneglycol (PEG)-conjugated substances lack immunogenicity and antigenic, it has been reported that they can elicit antibodies against PEG (mainly anti-PEG immunoglobulin M (IgM)). In patients, the presence of anti-PEG antibodies may limit therapeutic efficacy of PEGylated substances as a consequence of inducing rapid clearance of and neutraliz...

BACKGROUND The use of natural products based on aqueous extract of propolis and lycopene in the skin's protective mechanisms against UVA radiation was evaluated by means of experimental acute inflammation on rat paw edema. The aim of the present study was to evaluate the harmlessness of propolis - lycopene system through evaluation of skin level changes and anti-inflammatory action. The regener...

Immunohistochemistry (IHC) is an ancillary method, widely used in pathologist practice, that allows to identify diagnostic and prognostic/predictive therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies chromogenic substances guarantee visualization antibody–antigene binding complex under light microscope [...]