Sodium-glucose cotransporter-2 (SGLT2) inhibitors have become increasingly prescribed because of their proven protective effects on the heart and kidneys, carbohydrate-restricted diets are popular therapeutic approaches for patients with obesity diabetes. A 28-year-old obese woman recently diagnosed diabetes developed euglycemic diabetic ketoacidosis (DKA) while dapagliflozin, an SGLT2 inhibito...

The effects of ketone body metabolism suggests that mild ketosis may offer therapeutic potential in a variety of different common and rare disease states. These inferences follow directly from the metabolic effects of ketosis and the higher inherent energy present in d-beta-hydroxybutyrate relative to pyruvate, the normal mitochondrial fuel produced by glycolysis leading to an increase in the D...

Moderate low-carbohydrate/high-fat (LC-HF) diets are widely used to induce weight loss in overweight subjects, whereas extreme ketogenic LC-HF diets are used to treat neurological disorders like pediatric epilepsy. Usage of LC-HF diets for improvement of glucose metabolism is highly controversial; some studies suggest that LC-HF diets ameliorate glucose tolerance, whereas other investigations c...

Ketogenic diets are high in fat and low in carbohydrates and represent a well-established and effective treatment alternative to anti-epileptic drugs. Ketogenic diets are used for the management of a variety of difficult-to-treat or intractable seizure disorders, especially pediatric refractory epilepsy. However, it has been shown that this dietary therapy can reduce seizures in people of all a...

ARYA Journal 2006 (Fall); Volume 1, Issue 3 178 any chronically hypertensive patients tend to avoid drug treatment. Weight reduction, limitation of alcohol and dietary salt intake, vegetarian diets and doing aerobics are among factors which can reduce essential hypertension. Highpotassium and low-caffeine diets are also effective in hypertension control.1 The sympathetic nervous system is invol...

Four trials with pigs and one trial with rats were conducted to determine the relationship of dietary sugar level, supplemental vitamin K, sodium salicylate, therapeutic levels of chlortetracycline and initial pig weight to development of sugar-induced heart lesions and hemorrhagic syndrome. The effects of crude vs. refined sucrose and glucose vs. sucrose were also compared. Each of the high su...

Urolithiasis is defined as the formation of urolith or crystal in urinary tract caused by supersaturation urine. This study was conducted at PDHB drh Cucu Kartini S, dkk, Jakarta clinic. The data were taken from urinalysis test results 23 dogs which suffered crystaluria and stone examination 11 post cystotomy. Most affected breeds Shihtzu, Pug, Mini Pom, Corgi, Miniature Schnauzer, Golden Retri...

conclusions it was concluded that the efficacy of tramadol and fluoxetine in males with premature ejaculation are the same and both are effective. both of these drugs are safe to treat premature ejaculation. results thirty-six subjects with the mean age of 44 ± 19.3 years underwent analysis. eighteen subjects were treated by fluoxetine and 18 by tramadol. the efficacy of treatment in the two gr...

Cancer cells, relative to normal cells, demonstrate significant alterations in metabolism that are proposed to result in increased steady-state levels of mitochondrial-derived reactive oxygen species (ROS) such as O2(•-)and H2O2. It has also been proposed that cancer cells increase glucose and hydroperoxide metabolism to compensate for increased levels of ROS. Given this theoretical construct, ...