Unmet needs in urothelial cancer management represent an important challenge in our effort to improve long-term overall and disease-free survival rates with no significant compromise in quality of life. Radical cystectomy with pelvic lymph node dissection is the standard for the management of muscle-invasive, non-metastatic cancers. In spite of a 90% local disease control, up to 50% of patients...

Some might think science is a romantic endeavor. The classic ‘Edisonian’ lens of science has advanced precisely that vision: ‘the lone genius’. While this (false) metaphor of solitary scientific practice in a laboratory detached from society has prevailed for the past 400 years since the Enlightenment, ‘game changing’ transformative ideas do not hatch in a vacuum. Science and innovation are inh...

An insight into the intracellular fate of theranostics is important for improving their potential in biological applications. In vivo efficacy of plasmonic theranostics depends on our ability to monitor temporal changes in their size, shape, and state of aggregation, and the identification of molecules adsorbed on their surfaces. We develop a technique which combines plasmonic and Raman scatter...

One of the central directions of research in medical theranostics is the design of agents that can simultaneously exert a therapeutic effect and enable molecular imaging. Although several types of small molecules (e.g., radiotracers and photosensitizers (PS)) have been successfully used for disease-related theranostics, nanocarriers have a variety of advantages over small molecules, such as enh...

Cancer Theranostics In article number 2100029, Peng Huang and co-workers provide a periodic update emphasize on the potential applications of gold nanorods (GNRs) in diagnosis, cancer phototherapy, synergistic tumor therapy, imaging-guided therapy. The most recent advances GNRs research towards theranostics are highlighted.

Cancer is a major threat to human lives. Early detection and precisely targeted therapy/therapies for cancer the most effective way reduce difficulties (e.g., side effects, low survival rate, etc.) in treating cancer. To enable treatment, ceramic biomaterials have been intensively extensively investigated owing their good biocompatibility, high bioactivity, suitable biodegradability other disti...

Luminescent semiconductor nanocrystals, also known as quantum dots (QDs), have advanced the fields of molecular diagnostics and nanotherapeutics. Much of the initial progress for QDs in biology and medicine has focused on developing new biosensing formats to push the limit of detection sensitivity. Nevertheless, QDs can be more than passive bio-probes or labels for biological imaging and cellul...

Other SectionsAbstractINTRODUCTIONNANOTHERANOSTICSPHOTO-TRIGGERED THERANOSTICS IN CANCERCONCLUSION AND PERSPECTIVESReferences

Drug Free Tumor Theranostics In article number 2205165, Tymish Y. Ohulchanskyy and co-authors introduce hemoglobin nanocrystals for drug free, synergistic selective theranostics of colon cancer. After intravenous (i.v.) injection, these target tumor react with tumor-specific H2S H2O to enable magnetic resonance imaging guided photothermal therapy produce •OH chemodynamic therapy.