Vaults and telomerase are ribonucleoprotein (RNP) particles that share a common protein subunit, TEP1. Although its role in either complex has not yet been defined, TEP1 has been shown to interact with the mouse telomerase RNA and with several of the human vault RNAs in a yeast three-hybrid assay. An mTep1(-/-) mouse was previously generated which resulted in no apparent change in telomere leng...

OBJECTIVE To evaluate morphology and frequency of lower genital infections in (post hysterectomy) vault smears of women. METHODS We analyzed vault smears from 500 women who had undergone hysterectomy, either for benign diseases (230) or for carcinoma cervix (270) and findings were compared with Pap smear diagnosis of non-hysterectomy subjects. RESULTS Majority 432/500 (87%) of the vault sme...

personal authentication and identification as compared to the traditional authentication methods. Biometric templates are vulnerable to variety of attacks due to their inherent nature. When a person's biometric is compromised his identity is lost. In contrast to password, biometric is not revocable. Therefore, providing security to the stored biometric template is very crucial. Crypto biometric...

Vault is the largest nonicosahedral cytosolic nucleoprotein particle ever described. The widespread presence and evolutionary conservation of vaults suggest important biologic roles, although their functions have not been fully elucidated. X-ray structure of vault from rat liver was determined at 3.5 Å resolution. It exhibits an ovoid shape with a size of 40 × 40 × 67 nm(3). The cage structure ...

A 104-kD protein was coimmunoprecipitated with the estrogen receptor from the flowtrough of a phosphocellulose chromatography of MCF-7 cell nuclear extract. mAbs to this protein identified several cDNA clones coding for the human 104-kD major vault protein. Vaults are large ribonucleoprotein particles of unknown function present in all eukaryotic cells. They have a complex morphology, including...

The vault complex is a ubiquitous 13-MDa ribonucleoprotein assembly, composed of three proteins (TEP1, 240 kDa; VPARP, 193 kDa; and MVP, 100 kDa) that are highly conserved in eukaryotes and an untranslated RNA (vRNA). The vault has been shown to affect multidrug resistance in cancer cells, and one particular component, MVP, is thought to play a role in the transport of drug from the nucleus. To...

In this work we place some of the traditional biometrics work on fingerprint verification via the fuzzy vault scheme within a cryptographic framework. We show that the breaking of a fuzzy vault leads to decoding of Reed-Solomon codes from random errors, which has been proposed as a hard problem in the cryptography community. We provide a security parameter for the fuzzy vault in terms of the de...

Biometric techniques are gaining importance for personal authentication and identification as compared to the traditional authentication methods. Biometric templates are vulnerable to variety of attacks due to their inherent nature. When a person’s biometric is compromised his identity is lost. In contrast to password, biometric is not revocable. Therefore, providing security to the stored biom...

OBJECTIVE This article presents and discusses a new surgical abdominal technique for the treatment of posthysterectomy vaginal vault prolapse. METHOD It provides support of the peritoneal surface of the pelvic floor by means of a Gore-Tex mesh, which closes this space. The vaginal vault is fixed to the centre of the mesh. STUDY DESIGN Descriptive study. RESULTS Sixteen patients with vagin...