background: one of the most important heart diseases in dogs is valvular insufficiency, which can be evaluated by diagnosis ways such as phonocardiography, echocardiography, etc. objective: the purpose of the current study was to evaluate of valvular insufficiencies with phonocardiography and echocardiography and using phonocardiography technique in detection of cardiac valvular disease in prac...

pulmonary arterial hypertension (pah) is a progressive disease with high morbidity and mortality rates. research has shown that pah has a prevalence rate of 10-79% in thalassemia major patients. this cross-sectional study was carried out in 2014 to determine the prevalence and risk factors of pah in all thalassemia major patients of over 18 years of age in ilam, iran. a cardiologist measured sy...

background iron-loaded cardiac complication is the essential cause of mortality in patients with thalassemia. early detection and treatment of cardiac over-load can reduce mortality. objectives the current study aimed to evaluate the relationship between serum ferritin levels and t2* magnetic resonance imaging (mri) of heart and liver and liver iron concentration (lic) to diagnose iron over loa...

  Inroduction: Heart failure (HF) is an important cause of morbidity and mortality in the cases of Beta-thalassemia major. The purpose of this study was to estimate HF prevalence in these patients and to assess the survivability of those who were treated with intensive chelating therapy.   Design and methods: This cross sectional study included 72 beta-thalassemia major cases, the mean age at t...

  Background   Regarding abnormalities in thalassemia major (TM) patients and the effects of leptin and ferritin on heart, aimed to investigate the possible relationship between leptin, ferritin and cardiac involvement in TM patients compared to controls.   Materials and Methods   In total 141 individuals entered to the present case-control study that consisted of 66 TM patients matched in ag...

C heart disease (CHD) constitutes the majority of pediatric heart diseases and remains one of the major causes of morbidity and mortality. Previous studies demonstrated that CHD worldwide, is relatively common with a prevalence ranging from 4-50 per 1000 live births.1 The prevalence was 10.7 per 1000 in KSA2 in 2001, and 17.5 per 1000 in Central Australia3 in 2004. Only a few studies in Saudi A...

Background: Hydroxyurea (HU) is a well known chemotherapeutic agent that has been used largely for various myeloproliferative diseases over the past 20 years. In β-thalassemia, the effect of HU is much less clear and remains controversial. This study was undertaken to describe the hematologic and clinical responses of thalassemia major and intermediate patients to HU treatment during 2 years. M...

Background: Congenital heart diseases, which are asymptomatic at birth, are the most important causes of infant mortality. This study aimed to evaluate the role of pulse oximetry in the early detection of congenital heart diseases among newborns.Methods: In this cross-sectional descriptive study, 1230 newborns who were born in university hospitals in an urban area of Iran were placed unde...

bifid cardiac apex is a rare anomaly of human hearts. we report of the case of a 34-year-old man with a previous history of ventricular septal defect (vsd) and subvalvular pulmonary stenosis. he had undergone pulmonary commissurotomy and vsd closure 22 years before he was referred to our center for evaluation of progressive dyspnea. transthoracic echocardiography revealed atrial septal defect (...

in order to identify left ventricular diastolic function in patients with betathalassemia major and normal systolic function by noninvasive m-mode and doppler echocardiography, an analytic study was designed in a university hospital in sari. we have studied 44 patients (23 men and 21 women), mean age 15.48±2.16 (range 12 to 20) and 43 age and sex matched control subjects. peak flow velocity in ...