atavistic residues of aggressive behavior prevailing in animal life, determined by testosterone, remain attenuated in man and suppressed through familial and social inhibitions. however, it still manifests itself in various intensities and forms from; thoughts, anger, verbal aggressiveness, competition, dominance behavior, to physical violence. testosterone plays a significant role in the arous...

Background: Varicocele suggests that in addition to effects on spermatogenesis, varicocele also impairs testicular Leydig cell function with a consequential decrease in testosterone production; correction of the varicocele may result in improved serum testosterone levels. Materials and Methods: We measured preoperative serum testosterone levels in 40 infertile men with varicoceles varicocele (g...

objective: spinal cord injury (sci) causes infertility in male patients through erectile dysfunction, ejaculatory dysfunction, semen and hormone abnormalities. oxidative stress (os) is involved in poor semen quality and subsequent infertility in males with sci. the aim of this study is to examine the effects of sci on the level of testosterone hormone. materials and methods: in this experimenta...

This study aims to observe the effects of testosterone replacement therapy on glucose and lipid metabolism in middle-aged and elderly high-fat-fed male rats. This study established a high-fat-fed rat model and supplemented the rats with different doses of testosterone after castration. The rats were divided into control, complete lack of testosterone, low testosterone, medium testosterone, and ...

background: the secretion of thyroxin (t4) as the main hormone of thyroid gland is regulated by androgens. the present study aimed to evaluate the effect of testosterone and finasteride administration and castration on serum levels of t4 and to show the effect of this regulation on total body weight, weight of testis, and the weight of prostate. methods: male adult rats (n = 32) were divided in...

background: kisspeptin-gpr54 system stimulates the hypothalamus-pituitary-gonadal (hpg) axis; dysfunction of the gene encoding the gpr54 receptor causes hypogonadism and infertility. opioid peptides inhibit the reproductive axis. peptide 234 is a gpr54 receptor antagonist and blocks the stimulatory effects of kisspeptin on hpg axis. objectives: interactions of morphine, kisspeptin and peptide 2...

objective(s) the effect of testosterone on anxiety-like behaviors has been the subject of some studies. there is evidence that testosterone modulates anxiety via gaba (gama aminobutyric acid) and gabaergic system. the involvement of gabac receptors in those effects of testosterone on anxiety-like behaviors of the rats was investigated in the present study. materials and methods a group of rats ...

The pharmacokinetic characteristics of testosterone propionate were studied in normal men after a single im dose of 25 mg testosterone propionate-19,19,19-d3. Plasma levels of testosterone propionate-19,19,19-d3, its active metabolite testosterone-19,19,19-d3, and endogenous testosterone were measured by gas chromatography-mass spectrometry. Testosterone propionate-19,19,19-d3 was gradually tra...