BACKGROUND The use of plasma rich in growth factors (PRGF) has been proposed to improve the healing of Achilles tendon injuries, but there is debate about the effectiveness of this therapy. The objective of the present study was to evaluate the histological effects of PRGF, which is a type of leukocyte-poor platelet-rich plasma, on tendon healing. METHODS The Achilles tendons of twenty-eight ...

The predominant function of tendons is to position the limb during locomotion. Specific tendons also act as energy stores. Energy-storing (ES) tendons are prone to injury, the incidence of which increases with age. This is likely related to their function; ES tendons are exposed to higher strains and require a greater ability to recoil than positional tendons. The specialized properties of ES t...

Injured rat Achilles tendons were treated with botulism toxin to create a mechanically unloaded condition (unloaded) or left untreated (loaded), and then treated with phosphate-buffered saline (PBS), platelet-rich plasma (PRP), tendon stem cells (TSCs), or a combination (TSCs + PRP). mRNA and protein expression of collagen I, collagen III, tenascin C, and Smad 8 were determined by real time PCR...

10.1083/jcb/1722fta2jcb1722fta2Mitch [email protected] aking tendons C ells are fastidious about their internal conditions. But for scientists trying to decipher how collagen forms structures such as tendons and the cornea, the big question 30 years ago was how much control cells exert over their surroundings. In a tendon, for example, colla...

results the overall prevalence of right, left, bilateral and total absence of the palmaris longus were 4.1%, 5.2%, 3.9% and 13.2%, respectively. there was no significant difference in its absence with regard to the body side or gender (p > 0.05). background the palmaris longus is a degenerating weak flexor muscle in the anterior of the forearm. many techniques for clinically determining the pre...

Equine superficial digital flexor tendons (SDFT) are often injured, and they represent an excellent model for human sport tendinopathies. While lesions can be precisely diagnosed by clinical evaluation and ultrasonography, a prognosis is often difficult to establish; the knowledge of the injured tendon's mechanical properties would help in anticipating the outcome. The objectives of the present...

Tensile testing of repaired tendons has been used to assess the efficacy of repair techniques. However, individuals flex and extend fingers at rates higher than those typically used for testing. This study characterized the effect of loading rate on the failure strength of repaired canine flexor tendons. Thirty-six canine flexor digitorum profundus tendons were lacerated, repaired, and tested a...

Tendon injuries due to misuse or overuse as well as agerelated degeneration are common clinical problems facing orthopedic surgeons and sports medicine clinicians. Following injury, tendons exhibit an ineffective repair response that is often characterized by scar formation. Severe tendon injuries often require surgical intervention, but the structure and function of repaired tendons remain inf...

Acute rupture of flexor tendons following distal radius fracture is very rare. We experienced four cases of acute rupture of flexor tendons that were treated surgically. Injured tendons included flexor pollicis longus, flexor carpi radialis, palmaris longus and third flexor digitorum profundus. A severely displaced fracture with a volar spike of the distal radius was detected on plain radiograp...

A 59-year-old woman who had been diagnosed with heterozygous familial hypercholesterolemia developed rheumatoid arthritis (RA). She presented with marked tendinitis of the Achilles tendons, patellar tendons, and finger extensor tendons at the onset of RA. Ultrasonographic examination revealed that tendon lesions were predominantly tendinitis rather than paratenonitis, and that the tendinitis wa...