background clinical tendon injuries represent serious and unresolved issues of the case on how the injured tendons could be improved based on natural structure and mechanical strength. the aim of this studies the effect of aquatic activities and alogenic platelet rich plasma (prp) injection in healing achilles tendons of rats. methods forty rats were randomly divided into 5 equal groups. sevent...

Tendon never restores the complete biological and mechanical properties after healing. Several techniques are available for tissue-engineered biological augmentation for tendon healing like stem cells. Recently, synovium has been investigated as a source of cells for tissue engineering. In the present study, we investigated potentials of fibroblast like synoviocytes (FLSs) in tendon healing. Si...

Tendon never restores the complete biological and mechanical properties after healing. Bone marrow and recently adipose tissue have been used as the sources of mesenchymal stem cells, which have been proven to enhance tendon healing. Stromal vascular fraction (SVF), derived from adipose tissue by an enzymatic digestion, represents an alternative source of multipotent cells, which undergo differ...

In this study, the role of local injection of butyric acid (BA) with autogenous omental graft was evaluated in healing of experimental Achilles tendon injury in rabbits. Nine adult male New Zealand rabbits were anesthetized and a partial thickness tenotomy was created on both hindlimbs. In treated group, omental graft was secured in place using BA soaked polygalactin 910 suture. In control grou...

Sheep (and goats) are a convenient large-animal model for rotator cuff repair because of availability, ease of handling and housing, animal cost, and acceptance to society as a research animal. Tenotomy of the infraspinatus tendon and subsequent reattachment to the proximal humerus is useful to address the biomechanical, histologic, and biochemical processes of rotator cuff repair. Detaching th...

Purpose: Reporting the outcome of the modified peroneus brevis (PB) transfertechnique in treating 26 patients with chronic rupture of Achilles tendon (AT). Methods: The diagnosis was neglected acute AT rupture in ten patients, ten with achronic rupture, re-rupture of the tendon in four cases, and Achilles xanthoma in two cases. The gap after debridement was 6 cm in average (range 4-8). The tech...

INTRODUCTION Research on the mechanisms regulating tendon healing has predominantly focused on mechanical rather than biological features. Over the last decade, however, accumulating data suggests that besides cytokines and vascular factors also neuronal mediators are critical components of tissue repair. A variety of neuronal mediators, so called neuropeptides, have been identified and found t...

Introduction: The anterior cruciate ligament (ACL) is the most frequently injured ligament in the knee, often requiring surgical reconstruction. Central third bone-patellar tendon-bone (BPTB) autografts are commonly used for ACL reconstructions. Despite many advantages of the BPTB graft, harvesting of the graft often results in donor site morbidity including patellar baja and patellofemoral pai...

background autologous platelet concentrate has been used to improve the function and regeneration of injured tissues. tendinopathies are common in clinical practice, although long-term treatment is required. on the basis of lead time, we compared the effect of using platelet-rich plasma (prp) and platelet-rich fibrin (prf) in repairing rat achilles tendon. methods the effectiveness of using prp...