Blinatumomab, the bispecific T cell engager, has been demonstrated as the most successful BsAb to date. Throughout the past decade, vector design has great importance for the expression of monoclonal antibody in Chinese hamster ovary (CHO) cells. It has been indicated that expression plasmids based on the elongation factor-1 alpha (EF-1 alpha) gene and DHFR selection marker can be highly effect...

Blinatumomab, the bispecific T cell engager, has been demonstrated as the most successful BsAb to date. Throughout the past decade, vector design has great importance for the expression of monoclonal antibody in Chinese hamster ovary (CHO) cells. It has been indicated that expression plasmids based on the elongation factor-1 alpha (EF-1 alpha) gene and DHFR selection marker can be highly effect...

application of automatic systems, including discharge measurement technology is one of the effective methods for improving delivery management, water use efficiency, flexibility, and performance of irrigation networks. several aspects such as hydraulic, technical, physical, environmental, economic, social, and managerial, have significant impact on these systems selection. due to diversity of t...

Abstract: The competition in world market has intensified tremendously. Time to market a product is reduced considerably. Therefore, substantial reduction in time, methodology and material resources for development & production is required. Rapid Prototyping is a promising Time Compression technique. There are a large number of R.P. Technologies available in the market. Appropriate technology s...

The paper further develops the mathematical model of software design technology (SDT) and criteria for evaluating SDT, which allow experts to evaluate each considered more accurately, taking into account all its components. method production rules selection proposed by authors give organization opportunity make a motivated reasonable choice implementation

the main objective of this study was to understand of genetic association between quantitative and qualitative traits and also to quantify effects of selection for one trait on others in safflower. the study took place in the experimental field of the faculty of agriculture, isfahan university of technology, isfahan, iran, in the 2001 and 2002. to find the best variable for selection to improve...