purpose: to compare the effect of religious fasting on basal tear secretion (bts), tear break up time (tbt) and intraocular pressure (iop) in ramadan 2005. methods: one-hundred fifty-six healthy male volunteers less than 40 years of age from tehran, zahedan, ahvaz, mashhad and tabriz with no ocular and systemic disease participated in this study. weight, urine specific gravity, bts, tbt and iop...

OBJECTIVE To study electrical stimulation of the lacrimal gland and afferent nerves for enhanced tear secretion, as a potential treatment for dry eye disease. We investigate the response pathways and electrical parameters to safely maximize tear secretion. APPROACH We evaluated the tear response to electrical stimulation of the lacrimal gland and afferent nerves in isofluorane-anesthetized ra...

This paper is concerned with the recognition of the dry eye when the clinical diagnosis is in doubt and other external eye diseases may be present. Papillary conjunctivitis is common to the dry eye as well as other pathological conditions and confuses the diagnosis. We have correlated the factors involved in the assessment for dryness. We have shown that particulate matter in the unstained tear...

Modulation of lacrimal acinar cell tear secretion may involve multiple factors acting both in subtle and pronounced ways. Functional screens of recombinant protein products arising from gene array technologies, or protein fractions derived from lacrimal conditioned media or extracellular matrix, will require a highly sensitive assay capable of monitoring tear protein secretion by small replicat...

PURPOSE To evaluate the safety of bromfenac sodium eye drops from the standpoint of corneal sensitivity and tear secretion in healthy controls following instillation for 1 month. METHODS A prospective single-blind parallel clinical study was conducted in 20 eyes of ten healthy volunteers with no history of ocular or systemic allergic disease, dry eye, contact lens wear, or ocular surgery. Par...

The purpose of this study was to determine the prevalence of ocular surface disease symptoms and the state of the tear film among patients with glaucoma who are receiving topical intraocular pressure lowering monotherapy. 62 responders were divided in 2 groups: 32 glaucoma patients and 30 healthy individuals. Tear film break-up time (TBUT), Schirmer 1 testing and ocular surface disease question...

PURPOSE To analyze the levels of the diadenosine polyphosphates Ap4A and Ap5A in tears, in a set of control subjects and in groups of symptomatic and nonsymptomatic persons with dry eye. METHODS Ninety-seven subjects participated in the study. The subjects were divided into five experimental groups: control subjects; symptomatic patients with normal tear secretion; symptomatic patients with l...

purpose : to investigate tear film status after phacoemulsification surgery with temporal and supratemporal clear corneal incision in a cohort of patients with senile cataract methods : we enrolled sixty eight eyes of 68 patients with senile cataract requiring phacoemulsification in a prospective, cohort study. all patients undergone basic tear secretion test (btst), tear meniscus height (tmh),...