Purpose: To assess changes in the tear film and delayed drainage after upper or lower, combined punctal occlusion using dissolvable polydioxanone plugs patients with dry eye.Methods: In total, 40 eye (80 eyes) were enrolled: four groups of 10 (20 no, upper, lower occlusions. Dissolvable placed. The break-up time (tBUT) meniscus height (TMH) measured, Schirmer I test dye disappearance (DDT) perf...

Purpose. The continuous use of mask wear from pandemic induces instability in tear film due to the air blown up mask. study’s objective was assess effect type and duration, including short-term on TBUT. Design methods. This a cross-sectional, comparative study. A total 90 (180 eyes) subjects (76 females) were involved study categorized into three groups, each comprising 30 subjects. Either grou...

ocular dryness is a well-recognized adverse side effect of many topical and systemic medications. in psychiatry, patients who have consumed such drugs as lithium carbonate and sodium valproate frequently experience dry eye symptoms. the purpose of this study was to compare tear film stability between patients who use these drugs with those patients who are not on medication.after obtaining info...

INTRODUCTION There has been increased attention on the potential impact of the preservative benzalkonium chloride (BAK) on the ocular surface. This study compared the ocular surface tolerability of once-daily bimatoprost 0.01% and latanoprost 0.005% (both preserved with 0.02% BAK), and travoprost 0.004% preserved with sofZia™. METHODS A randomized, multicenter (15 sites), investigator-masked ...

PURPOSE To evaluate the efficacy and safety of two ophthalmic solutions in patients with mild to moderate dry eye. METHODS We performed a prospective, 2-month-long, randomized, double-blind, single-center, parallel clinical trial to compare the efficacy and safety of two ophthalmic solutions for dry eye treatment. Patients were randomly assigned to one of the two treatment groups, study group...

PURPOSE This study compares signs, symptoms and predictive tools used to diagnose dry eye disease (DED) and ocular surface disorders in six systemic well-defined and non-overlapping diseases. It is well known that these tests are problematic because of a lack of agreement between them in identifying these conditions. Accordingly, we provide here a comparative clinical profile analysis of these ...

INTRODUCTION Benzalkonium chloride (BAK), included as a preservative in many topical treatments for glaucoma, induces significant toxicity and alters tear breakup time (TBUT). BAK-containing latanoprost, an ester prodrug of prostaglandin F2α, can cause ocular adverse events (AEs) associated with BAK. The purpose of this study was to evaluate the efficacy and safety of BAK-free latanoprost. PA...

PURPOSE To assess the effect of oral re-esterified omega-3 fatty acids on tear osmolarity, matrix metalloproteinase-9 (MMP-9), tear break-up time (TBUT), Ocular Surface Disease Index (OSDI), fluorescein corneal staining, Schirmer score, meibomian gland dysfunction (MGD) stage and omega-3 index in subjects with dry eyes and confirmed MGD. METHODS This was a multicenter, prospective, interventi...

AIM: To evaluate the efficacy and tolerability of administering a combined therapy in patients with dry eye syndrome (DES) associated laryngopharyngeal reflux (LPR). METHODS: The study was retrospective, open, observational, conducted real-life setting. Patients had pathological symptom assessment (SANDE) index (RSI) at baseline. were re-assessed after 1mo end treatment. treatment consisted thr...